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GIMAP5 is a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene.
Gene Name: | GTPase, IMAP family member 5 |
Synonyms: | GIMAP5, GTPase IMAP family member 5, HIAN5, HIMAP3, IMAP3, Immunity-associated protein 3, IROD, IAN-5, Ian4, IAN4L1, IAN5, GTPase, IMAP family member 5, Immunity associated protein 3 |
Target Sequences: | NM_018384 NP_060854.2 Q96F15 |
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