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GHSR / Ghrelin Receptor

growth hormone secretagogue receptor

GHSR / Ghrelin Receptor is a member of the G-protein coupled receptor family. The encoded protein may play a role in energy homeostasis and regulation of body weight. Two identified transcript variants are expressed in several tissues and are evolutionary conserved in fish and swine. One transcript, 1a, excises an intron and encodes the functional protein; this protein is the receptor for the Ghrelin ligand and defines a neuroendocrine pathway for growth hormone release. The second transcript (1b) retains the intron and does not function as a receptor for Ghrelin; however, it may function to attenuate activity of isoform 1a. Mutations in this gene are associated with autosomal idiopathic short stature.

Gene Name: growth hormone secretagogue receptor
Family/Subfamily: GPCR , Releasing hormone
Synonyms: GHSR, GHS receptor, GH secretagogue receptor, GHRP, GHS-R, GH-releasing peptide receptor, Ghrelin receptor, Ghrp receptor
Target Sequences: NM_198407 AAC50653.1 Q92847

Publications (2)

1
Electroacupuncture improves acute bowel injury recovery in rat models. Wu J, Lyu B, Gan T, Wang L, Zhu M. Experimental and therapeutic medicine. 2017 14:4655-4662. (WB; Human) [Full Text Article] [PubMed:29201164] Related Antibodies: LS-C136920.
2
Characterization of a Monoclonal Antibody Specific for the Growth Hormone Secretagogue Receptor. Crotta K, Casnici C, Tonna N, Lattuada D, Bianco F, Marelli O. Monoclonal antibodies in immunodiagnosis and immunotherapy. 2017 36:37-43. (WB; Human) [Full Text Article] [PubMed:28409695]

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
GHSR / Ghrelin Receptor (3)
No (3)
GST (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
GHSR / Ghrelin Receptor Protein - 12.5% SDS-PAGE of human GHSR stained with Coomassie Blue
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Wheat Germ Extract
GST
58.6 kDa
10 µg/$479; 25 µg/$670
GHSR / Ghrelin Receptor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
32 kDa
100 µg/$494
GHSR / Ghrelin Receptor Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
32 kDa
20 µg/$150
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).