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GGT6 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).
Gene Name: | gamma-glutamyltransferase 6 |
Synonyms: | GGT6, Gamma-glutamyltranspeptidase 6, Gamma-glutamyltransferase 6, Glutathione hydrolase 6, GGT 6 |
Target Sequences: | AA923594 |
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