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GGT2 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).
Gene Name: | gamma-glutamyltransferase 2 |
Synonyms: | GGT2, Gamma-glutamyltranspeptidase 2, GGT, GGT 2, Gamma-glutamyltransferase 2, Glutathione hydrolase 2 |
Target Sequences: | XP_001129425.1 P36268 |
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