GFRA2

GDNF family receptor alpha 2

Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN), play key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to NTN require the presence of a novel glycosylphosphadidylinositol linked protein NTNRa, which is a cell surface receptor for NTN. The cDNAs encoding NTNRa from human, rat, chicken, and mouse have been cloned recently (2-7). NTNRa was also termed GDNFRb, Ret ligand 2 (RETL2) or TGF-b-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRa-2 recently. GFRa-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRa-2, and the Ret PTK form a complex to transduce NTN signal and to mediate NTN function.

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Products

Proteins (11)

Type

Over-Expression Lysate (4)

Recombinant (7)

Target

GFRA2 (11)

Publications

No (11)

Tag

6His, C-terminus (2)

Fc-6His, C-terminus (1)

His (1)

His-T7 (2)

Myc-DDK (Flag) (4)

Species

Human (7)

Mouse (2)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (2)

Human Cells (3)

Mammalian Cells (2)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (5)

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GFRA2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G128072

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.5 kDa

Price:

100 µg/$494

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Human GFRA2 Protein (Recombinant His-T7) (aa117-314) - LS-G24656

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.1 kDa

Price:

10 µg/$246; 50 µg/$299; 100 µg/$352; 200 µg/$442; 1 mg/$1,242; 500 µg/$882; 5 mg/$2,097; 2 mg/$1,391

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Mouse GFRA2 Protein (Recombinant His-T7) (aa117-314) - LS-G24657

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.2 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human GFRA2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77683

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.54 kDa

Price:

20 µg/$150

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Human GFRA2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77684

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.5 kDa

Price:

20 µg/$150

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GFRA2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99457

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.54 kDa

Price:

100 µg/$494

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Human GFRA2 Protein (Recombinant 6His, C-terminus) (Ser22-Ser441) - LS-G38981

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

47.79kD

Price:

10 µg/$240; 50 µg/$299; 500 µg/$929; 1 mg/$1,245

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Human GFRA2 Protein (Recombinant Fc-6His, C-terminus) (Ser22-Ser441) - LS-G39992

Source:

Human Cells

Tag:

Fc-6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

74.7kD

Price:

10 µg/$248; 50 µg/$288; 500 µg/$785; 1 mg/$1,203

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Human GFRA2 Protein (Recombinant) (Ser22-Ser441) - LS-G138620

Source:

Mammalian Cells

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

74.7 kDa

Price:

10 µg/$248; 50 µg/$288

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Human GFRA2 Protein (Recombinant 6His, C-terminus) (Ser22-Ser441) - LS-G138663

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

47.8 kDa

Price:

10 µg/$240; 50 µg/$299

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Mouse GFRA2 Protein (Recombinant His) (Met1-Ser441) - LS-G98788

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

48.5 kDa

Price:

100 µg/$926

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