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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GFRA1 / GFR Alpha

GDNF family receptor alpha 1

Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons and is essential for the development of kidneys and the enteric nerves system. Physiological responses to GDNF require the presence of a novel glycosylphosphadidylinositol linked protein GDNFRa, which is a cell surface receptor for GDNF. The cDNAs encoding GDNFRa from human, rat, chicken and mouse have been cloned recently. GDNFRa was also termed Ret ligand 1 (RETL1) or TGF-b-related neurotrophic factor receptor 1 (TrnR1) and nominated as GFRa-1 recently. GFRa-1 binds GDNF specifically and mediates activation of the Ret protein tyrosine kinase (PTK). Thus, GDNF, GFRa and the Ret PTK form a complex to transduce GDNF signal and to mediate GDNF function.

Gene Name: GDNF family receptor alpha 1
Family/Subfamily: GDNF Receptor , Not assigned-Other
Synonyms: GFRA1, GDNF receptor alpha-1, GDNFRA, GFR-ALPHA-1, GDNF family receptor alpha-1, GDNFR, GDNFR-alpha-1, RET ligand 1, RETL1, TRNR1, RET1L, GDNF family receptor alpha 1, GPI-linked anchor protein
Target Sequences: NM_005264 NP_005255.1 P56159

Filtered by: None
Target
GFRA1 / GFR Alpha (43)
Reactivity
Human (28)
Mouse (26)
Rat (15)
Pig (8)
Application
IHC (16)
IHC-P (7)
WB (31)
ELISA (16)
IF (4)
Peptide-ELISA (1)
Host
rabbit (42)
mouse (1)
Isotype
IgG (16)
IgG2a,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (42)
Clone
1G4 (1)
Format
AP Conjugated (1)
APC (2)
APC Conjugated (2)
Biotin Conjugated (4)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (3)
Unconjugated (21)
Epitope
aa239-350 (16)
30-110 aa, Internal (1)
Lys90 (1)
aa25-227 (1)
aa369-382 (1)
aa51-100 (1)
Publications
No (43)
Showing 1-25 of 43 results

IHC-plus™ GFRA1 / GFR Alpha Antibody (aa239-350) LS-B14620
Rabbit Polyclonal to Human GFRA1 / GFR Alpha
Pig, Human
IHC, IHC-P, WB
Unconjugated
100µl 0.5mg/ml  $485.00
Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot of recombinant Human GFRA1 / GFR Alpha.

GFRA1 / GFR Alpha Antibody LS-C264
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.1mg 1mg/ml  $365.00
Immunohistochemistry of GFRa-1 in human brain tissue with GFRa-1 antibody at 1 µg/ml.
Immunofluorescence of GFR alpha 1 in human brain tissue with GFR alpha 1 antibody at 20 ug/mL.  Red: GFR alpha 1 Antibody  Blue: DAPI staining

GFRA1 / GFR Alpha Antibody LS-C334020
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Human
IF, IHC, WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunofluorescence analysis of U20S cell using GFRA1 antibody. Blue: DAPI for nuclear staining.
Western blot analysis of extracts of various cell lines, using GFRA1 antibody at a 1:1000 dilution.

GFRA1 / GFR Alpha Antibody (clone 1G4) LS-C197291
Mouse Monoclonal [clone 1G4] (IgG2a,k) to Human GFRA1 / GFR Alpha
Human
ELISA, IF, WB
Unconjugated
100µg  $365.00
Immunofluorescence of monoclonal antibody to GFRA1 on HeLa cell . [antibody concentration 10 ug/ml]

GFRA1 / GFR Alpha Antibody LS-C498906
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human breast cancer using GFRA1 Antibody at dilution of 1:100
Immunofluorescent analysis of A549 cells using GFRA1 Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

GFRA1 / GFR Alpha Antibody LS-C662389
Rabbit Polyclonal to Human GFRA1 / GFR Alpha
Human
IHC, IHC-P, WB
Unconjugated
100µg  $325.00
Immunohistochemistry - Anti-GFRA1/Gfr Alpha 1 Picoband Antibody
anti-GFRA1 antibody IHC(P): Human Lung Cancer Tissue

GFRA1 / GFR Alpha Antibody LS-C806624
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Western blot Image

GFRA1 / GFR Alpha Antibody LS-C486671
Rabbit Polyclonal to Mouse GFRA1 / GFR Alpha
Mouse
ELISA, IHC, IHC-P
Unconjugated
50µl  $275.00; 100µl  $355.00

GFRA1 / GFR Alpha Antibody (aa25-227) LS-C388490
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Human
IHC, IHC-P, WB
Unconjugated
100µg  $435.00
IHC-P: GFRA1 antibody testing of human lung cancer tissue
Western blot testing of GFRA1 antibody and recombinant human protein (0.5ng)

GFRA1 / GFR Alpha Antibody (30-110 aa, Internal) LS-C383678
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
ELISA, IHC
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00

GFRA1 / GFR Alpha Antibody (aa51-100) LS-C118456
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using GFR alpha-1 Antibody. The picture on the right is blocked with the synthesized peptide.

GFRA1 / GFR Alpha Antibody LS-C486669
Rabbit Polyclonal to Mouse GFRA1 / GFR Alpha
Mouse
ELISA, WB
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00

GFRA1 / GFR Alpha Antibody (Lys90) LS-C176037
Rabbit Polyclonal to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
IHC, IHC-P
Unconjugated
100µl  $345.00
IHC of GFR -1 (K90) pAb in paraffin-embedded human brain tissue.

GFRA1 / GFR Alpha Antibody LS-C405619
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
ELISA, WB
Unconjugated
20µl 0.6mg/ml  $205.00; 60µl 0.6mg/ml  $235.00; 120µl 0.6mg/ml  $295.00; 200µl 0.6mg/ml  $395.00
Western blot analysis of 293T cell, using GFRA1 Polyclonal Antibody at dilution of 1:1250.

GFRA1 / GFR Alpha Antibody (HRP) LS-C546338
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
IHC, WB
HRP Conjugated
100µl  $770.00

GFRA1 / GFR Alpha Antibody (Biotin) LS-C526226
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
IHC, WB
Biotin Conjugated
100µl  $770.00

GFRA1 / GFR Alpha Antibody (FITC) LS-C536229
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
IHC, WB
FITC Conjugated
100µl  $770.00

GFRA1 / GFR Alpha Antibody (PE) LS-C654408
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
IHC, WB
PE Conjugated
100µl  $770.00

GFRA1 / GFR Alpha Antibody (AP) LS-C508239
Rabbit Polyclonal (IgG) to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
IHC, WB
AP Conjugated
100µl  $770.00

GFRA1 / GFR Alpha Antibody LS-C486667
Rabbit Polyclonal to Mouse GFRA1 / GFR Alpha
Mouse
ELISA
Unconjugated
50µl  $275.00; 100µl  $355.00

GFRA1 / GFR Alpha Antibody LS-C486670
Rabbit Polyclonal to Mouse GFRA1 / GFR Alpha
Mouse
ELISA
Unconjugated
100µl  $255.00; 200µl  $305.00; 400µl  $355.00

GFRA1 / GFR Alpha Antibody (aa239-350) LS-C374978
Rabbit Polyclonal to Mouse GFRA1 / GFR Alpha
Mouse
WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $275.00; 200µl 0.5mg/ml  $315.00; 1ml 0.5mg/ml  $590.00
Western blot of GFRA1 / GFR Alpha antibody.

GFRA1 / GFR Alpha Antibody (aa239-350, Biotin) LS-C689386
Rabbit Polyclonal to Mouse GFRA1 / GFR Alpha
Mouse
WB
Biotin Conjugated
100µl 0.5mg/ml  $285.00; 200µl 0.5mg/ml  $335.00; 1ml 0.5mg/ml  $650.00
Western blot of GFRA1 / GFR Alpha antibody.

GFRA1 / GFR Alpha Antibody (aa239-350, FITC) LS-C696492
Rabbit Polyclonal to Mouse GFRA1 / GFR Alpha
Mouse
WB
FITC Conjugated
100µl 0.5mg/ml  $295.00; 200µl 0.5mg/ml  $355.00; 1ml 0.5mg/ml  $710.00
Western blot of GFRA1 / GFR Alpha antibody.

GFRA1 / GFR Alpha Antibody (aa369-382) LS-C48979
Rabbit Polyclonal to Human GFRA1 / GFR Alpha
Mouse, Rat, Human
WB
Unconjugated
100µg 200µl  $425.00
Showing 1-25 of 43 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).