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GFPT1 / GFAT

glutamine--fructose-6-phosphate transaminase 1

Glutamine-fructose-6-phosphate transaminase 1 is the first and rate-limiting enzyme of the hexosamine pathway. GFAT controls the flux of glucose into the hexosamine pathway and catalyzes the formation of glucosamine 6-phosphate.

Gene Name: glutamine--fructose-6-phosphate transaminase 1
Synonyms: GFPT1, GFA, GFPT, GFAT, GFAT1, GFAT1m, MSLG, CMSTA1, GFAT 1, GFPT1L
Target Sequences: NM_002056 NP_002047.2 Q06210

Publications (1)

1
Glycolysis and glutaminolysis cooperatively control T cell function by limiting metabolite supply to N-glycosylation. Araujo L, Khim P, Mkhikian H, Mortales CL, Demetriou M. eLife. 2017 6: (WB; Human) [Full Text Article] [PubMed:28059703] [PMC:PMC5257256]

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).