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GDNF

glial cell derived neurotrophic factor

GDNF is a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease.

Gene Name: glial cell derived neurotrophic factor
Family/Subfamily: TGF beta , not assigned-TGF beta
Synonyms: GDNF, HSCR3, HFB1-GDNF, ATF, HGDNF
Target Sequences: NM_000514 NP_000505.1 P39905

☰ Filters
Products
Proteins (29)
Over-Expression Lysate (8)
Recombinant (21)
GDNF (29)
Animal-free (3)
No (29)
6His, C-terminus (1)
GST (1)
GST, N-terminus (1)
His (4)
His, N-Terminal (1)
His-SUMO (1)
Myc-DDK (Flag) (8)
Human (17)
Mouse (4)
Rat (3)
Rhesus monkey (1)
293T Cells (4)
CHO Cells (1)
E. coli (17)
HEK 293 Cells (4)
Human Cells (1)
Wheat Germ Extract (2)
Purified (10)
Low endotoxin level (13)
Biologically active (10)
Animal-free (3)
Select
CHO Cells
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
17-22 kDa (SDS-PAGE)
5 µg/$278; 25 µg/$381
GDNF Protein
Select
E. coli
His-SUMO
31.1 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
GDNF Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
2 µg/$439
Select
293T Cells
Myc-DDK (Flag)
23.72 kDa
20 µg/$150
GDNF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
23.72 kDa
20 µg/$150
GDNF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
14.6 kDa
20 µg/$150
GDNF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
18.8 kDa
20 µg/$150
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
15.1 kDa-30.2 kDa
2 µg/$268; 10 µg/$349
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
15.1 kDa-30.2 kDa
2 µg/$282; 10 µg/$370
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
15 kDa
2 µg/$268; 10 µg/$349
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
2 µg/$282; 10 µg/$370
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
15 kDa
2 µg/$268; 10 µg/$349
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
2 µg/$281; 10 µg/$369
Select
E. coli
None
Biologically active
30.1 kDa
10 µg/$388; 100 µg/$1,466; 500 µg/$3,025
GDNF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
18.8 kDa
100 µg/$494
GDNF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
14.6 kDa
100 µg/$494
GDNF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
23.72 kDa
100 µg/$494
GDNF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
23.72 kDa
100 µg/$494
GDNF Protein - 12.5% SDS-PAGE of human GDNF stained with Coomassie Blue
Select
Wheat Germ Extract
GST
50.1 kDa
2 µg/$439
GDNF Protein - Recombinant Glial Cell Line Derived Neurotrophic Factor By SDS-PAGE
Select
E. coli
His
16.3 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
GDNF Protein - Recombinant Glial Cell Line Derived Neurotrophic Factor By SDS-PAGE
Select
E. coli
His
16.9 kDa
10 µg/$281; 50 µg/$440; 100 µg/$702; 200 µg/$877; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170
GDNF Protein - Recombinant Glial Cell Line Derived Neurotrophic Factor By SDS-PAGE
Select
E. coli
His
16.2 kDa
10 µg/$287; 50 µg/$480; 100 µg/$767; 200 µg/$957; 1 mg/$2,089; 500 µg/$1,617; 5 mg/$3,347; 2 mg/$2,278
Select
E. coli
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
17 kDa
1 mg/$2,653; 10 µg/$296; 50 µg/$478
GDNF Protein
Select
E. coli
His, N-Terminal
17 kDa
10 µg/$265; 100 µg/$365; 250 µg/$518; 50 µg/$315; 500 µg/$949
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
15.1 kDa
20 µg/$360; 100 µg/$728
Viewing 1-25 of 29 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).