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Glycosyltransferase that catalyzes the transfer of an N-acetylglucosamine moiety onto mucin-type core 1 O-glycan to form the branched mucin-type core 2 O-glycan. Mucin-type core 2 O-glycans play an important role in leukocyte extravasation as they serve as scaffolds for the display of the selectin ligand sialyl Lewis X by leukocytes.
Gene Name: | glucosaminyl (N-acetyl) transferase 1, core 2 |
Synonyms: | GCNT1, C2GNT, C2GNT-L, C2GNT1, Core 2-branching enzyme, Core2-GlcNAc-transferase, Core 2 branching enzyme, Core 2 GNT, G6NT, NACGT2, NAGCT2 |
Target Sequences: | NM_001490 NP_001481.2 Q02742 |
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