LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us

GCLC

glutamate-cysteine ligase, catalytic subunit

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.

Gene Name: glutamate-cysteine ligase, catalytic subunit
Synonyms: GCLC, GCL, GCS heavy chain, Gamma-ECS, GCS, GLCL, GLCLC
Target Sequences: NM_001498 NP_001489.1 P48506

Filtered by: None
Target
GCLC (67)
Reactivity
Human (47)
Mouse (41)
Rat (27)
Bat (7)
Bovine (10)
Chicken (3)
Chimpanzee (6)
Dog (7)
Drosophila (3)
Gibbon (3)
Guinea pig (7)
Hamster (4)
Horse (3)
Monkey (12)
Pig (7)
Rabbit (8)
Xenopus (3)
Zebrafish (8)
Application
IHC (45)
IHC-P (13)
WB (67)
Flo (8)
ELISA (19)
ICC (6)
IF (9)
IP (4)
Host
rabbit (65)
mouse (2)
Isotype
IgG (25)
IgG1 (1)
IgG1,k (1)
Clonality
monoclonal mc (2)
polyclonal pc (65)
Clone
1A3 (1)
3H1 (1)
Format
AP Conjugated (2)
APC (3)
APC Conjugated (5)
Azide-free (3)
Biotin Conjugated (10)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (10)
HRP Conjugated (7)
PE Conjugated (5)
Unconjugated (22)
Epitope
aa435-636 (20)
aa429-637 (10)
aa1-30 (8)
aa286-315 (8)
aa74-123 (4)
aa323-372 (3)
Internal (2)
Glu315 (1)
aa1-214 (1)
aa295-313 (1)
aa437-637 (1)
aa7-24 (1)
Publications
No (67)
Showing 1-25 of 67 results

GCLC Antibody (aa295-313) IHC-plus™ LS-B2328
Rabbit Polyclonal to Rat GCLC
Mouse, Bovine, Rat, Human, Monkey
ELISA IHC IHC-P IP WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-GCLC antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

GCLC Antibody (aa1-30) LS-C166412
Rabbit Polyclonal to Human GCLC
Human
Flo IF IHC IHC-P WB
Unconjugated
400µl  $325.00
GCLC Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human esophageal carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
Confocal immunofluorescence of GCLC Antibody with U-251MG cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

GCLC Antibody (aa286-315) IHC-plus™ LS-B11794
Rabbit Polyclonal to Human GCLC
Mouse, Human
IHC IHC-P WB
Unconjugated
200µl  $425.00
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

GCLC Antibody (aa437-637) LS-C344053
Rabbit Polyclonal to Human GCLC
Rat, Human
IHC IHC-P WB
Unconjugated
100µg 200µl 0.5mg/ml  $355.00
GCLC antibody IHC-paraffin: Human Lung Cancer Tissue.
GCLC antibody IHC-paraffin: Human Mammary Cancer Tissue.

GCLC Antibody (aa323-372, FITC) LS-C458773
Rabbit Polyclonal to Human GCLC
Xenopus, Chicken, Zebrafish, Drosophila, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
IHC IHC-P WB
FITC Conjugated
100µl 1mg/ml  $405.00
Anti-GCLC antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
GCLC antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

GCLC Antibody (aa1-30) LS-C321586
Rabbit Polyclonal (IgG) to Human GCLC
Human
ELISA Flo IF IHC WB
Unconjugated
200µl  $590.00

GCLC Antibody (aa1-30, Biotin) LS-C214656
Rabbit Polyclonal (IgG) to Human GCLC
Human
ELISA Flo ICC IF IHC WB
Biotin Conjugated
200µl  $740.00

GCLC Antibody (aa1-30, FITC) LS-C214657
Rabbit Polyclonal (IgG) to Human GCLC
Human
ELISA Flo ICC IF IHC WB
FITC Conjugated
200µl  $740.00

GCLC Antibody (aa1-30, APC) LS-C214655
Rabbit Polyclonal (IgG) to Human GCLC
Human
ELISA Flo ICC IF IHC WB
APC Conjugated
200µl  $740.00

GCLC Antibody (aa1-30, AP) LS-C214654
Rabbit Polyclonal (IgG) to Human GCLC
Human
ELISA Flo ICC IF IHC WB
AP Conjugated
200µl  $740.00

GCLC Antibody (aa1-30, Azide-free, HRP) LS-C214659
Rabbit Polyclonal (IgG) to Human GCLC
Human
ELISA Flo ICC IF IHC WB
HRP Conjugated, Azide-free
200µl  $740.00

GCLC Antibody (aa1-30, PE) LS-C214661
Rabbit Polyclonal (IgG) to Human GCLC
Human
ELISA Flo ICC IF IHC WB
PE Conjugated
200µl  $740.00

GCLC Antibody (aa74-123) IHC-plus™ LS-B5844
Rabbit Polyclonal (IgG) to Human GCLC
Zebrafish, Pig, Bat, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Human, Monkey
IHC IHC-P WB
Unconjugated
100µl  $485.00
Anti-GCLC antibody IHC of human brain-cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Fetal liver lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

GCLC Antibody (clone 3H1) LS-C197304
Mouse Monoclonal [clone 3H1] (IgG1,k) to Human GCLC
Human
ELISA IF WB
Unconjugated
100µg  $355.00
Immunofluorescence of monoclonal antibody to GCLC on HeLa cell. [antibody concentration 10 ug/ml]
GCLC monoclonal antibody (M01), clone 3H1 Western Blot analysis of GCLC expression in A-431.

GCLC Antibody (clone 1A3) LS-C338473
Mouse Monoclonal [clone 1A3] (IgG1) to Human GCLC
Rat, Human, Monkey
IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $345.00
IHC of paraffin-embedded Human pancreas tissue using anti-GCLC mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
IHC of paraffin-embedded Carcinoma of Human thyroid tissue using anti-GCLC mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

GCLC Antibody LS-C752502
Rabbit Polyclonal (IgG) to Human GCLC
Human
ELISA IHC IP WB
Unconjugated
100µg  $335.00

GCLC Antibody (aa435-636) LS-C294231
Rabbit Polyclonal to Rat GCLC
Mouse, Rat
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $265.00; 200µl 0.5mg/ml  $315.00; 1ml 0.5mg/ml  $575.00; 10ml 0.5mg/ml  $2,280.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

GCLC Antibody (aa435-636, HRP) LS-C737843
Rabbit Polyclonal to Rat GCLC
Mouse, Rat
IHC WB
HRP Conjugated
100µl 0.5mg/ml  $295.00; 200µl 0.5mg/ml  $355.00; 1ml 0.5mg/ml  $740.00; 10ml 0.5mg/ml  $2,955.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

GCLC Antibody (aa435-636, Cy3) LS-C703695
Rabbit Polyclonal to Rat GCLC
Mouse, Rat
IHC WB
Cy3 Conjugated
100µl 0.5mg/ml  $375.00; 200µl 0.5mg/ml  $465.00; 1ml 0.5mg/ml  $1,140.00; 10ml 0.5mg/ml  $4,560.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

GCLC Antibody (aa435-636, APC) LS-C718422
Rabbit Polyclonal to Rat GCLC
Mouse, Rat
IHC WB
APC Conjugated
100µl  $315.00; 200µl  $385.00; 1ml  $860.00; 10ml  $3,930.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

GCLC Antibody (aa435-636, PE) LS-C726779
Rabbit Polyclonal to Rat GCLC
Mouse, Rat
IHC WB
PE Conjugated
100µl  $285.00; 200µl  $345.00; 1ml  $680.00; 10ml  $2,730.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

GCLC Antibody (aa435-636, APC, Cy7) LS-C735701
Rabbit Polyclonal to Rat GCLC
Mouse, Rat
IHC WB
APC, Cy7 Conjugated
100µl  $475.00; 200µl  $680.00; 1ml  $1,710.00; 10ml  $6,840.00
Immunohistochemistry - Paraffin Image
Immunohistochemistry - Paraffin Image

GCLC Antibody (aa435-636) LS-C294229
Rabbit Polyclonal to Mouse GCLC
Mouse
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $265.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $545.00; 10ml 0.5mg/ml  $2,160.00
Immunohistochemistry - Paraffin Image
Western blot of recombinant GCLC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

GCLC Antibody (aa7-24) LS-C312650
Rabbit Polyclonal to Human GCLC
Rabbit, Human, Monkey
IHC IHC-P WB
Unconjugated
100µg 200µl 0.5mg/ml  $355.00
GCLC antibody. IHC(P): Human Rectal Cancer Tissue.
WB of GCLC antibody. Lane 1: Rat Brain Tissue Lysate. Lane 2: Rat Kidney Tissue Lysate. Lane 3: Rat Heart Tissue Lysate. Lane 4: Rat Lung Tissue Lysate.

GCLC Antibody (aa429-637) LS-C294230
Rabbit Polyclonal to Human GCLC
Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $530.00; 10ml 0.5mg/ml  $2,100.00
Immunohistochemistry - Paraffin Image
Western blot of recombinant GCLC.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Showing 1-25 of 67 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

Get Social With Us!
Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2019 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy