Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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Unfortunately, the ELISA kit (ID:26608) is no longer available.
Below is a list of ELISA kits to the same protein target. You may also try your search again using the search box at the top of the page.
Please contact us if you have any questions.
GCGR / Glucagon Receptor
The Glucagon Receptor mediates the effects of glucagon in controlling glucose metabolism by initiating a cascade of events that regulate the amount of glucose released from the liver into the bloodstream. Glucagon generally functions as a counterregulatory hormone, opposing the actions of insulin, in maintaining the levels of blood glucose, particularly in patients with hypoglycemia. In patients with diabetes, excess glucagon secretion plays a primary role in the metabolic perturbations associated with diabetes, such as hyperglycemia. Glucagon knockout mice exhibit reduced glood glucose levels, improved glucose tolerance, elevated blood glucagon levels, and normal insulin levels. Despite a total absence of glucagon receptors, these animals maintained near-normal glycemia and normal lipidemia, in the presence of circulating glucagon concentrations that were elevated by two orders of magnitude. A missense mutation (Gly40Ser) in the glucagon receptor gene is associated with non-insulin-dependent diabetes mellitus.