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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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Gastrin Releasing Peptide
gastrin-releasing peptide
Gastrin Releasing Peptide is a member of the bombesin-like family of gastrin-releasing peptides. Its preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27 aa gastrin-releasing peptide or the 10 aa neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants encoding different isoforms.
| Gene Name: | gastrin-releasing peptide |
| Family/Subfamily: | Bombesin-like peptide , not assigned-Bombesin-like peptide |
| Synonyms: | GRP, BN, Bombesin, Gastrin-releasing peptide, Neuromedin C, ProGRP, GRP-10, PreproGRP |
| Target Sequences: | NM_002091 NP_002082.2 P07492 |
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