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GABRE belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants have been identified, but only one is thought to encode a protein.
Gene Name: | gamma-aminobutyric acid (GABA) A receptor, epsilon |
Family/Subfamily: | Ion Channel , GABA A receptor |
Synonyms: | GABRE, GABA receptor epsilon, GABA(A) receptor, epsilon |
Target Sequences: | NM_021987 NP_004952.2 P78334 |
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