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GABRA6

gamma-aminobutyric acid (GABA) A receptor, alpha 6

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABA-A receptor subtype. GABA-A receptors are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABA-A receptor is a multimeric subunit complex. To date six alpha, four beta, and four gamma subunits, plus alternative splicing variants of some of these subunits, have been identified. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor.

Gene Name: gamma-aminobutyric acid (GABA) A receptor, alpha 6
Family/Subfamily: Ion Channel , GABA A receptor
Synonyms: GABRA6, GABA A receptor alpha 6, GABA(A) receptor, alpha 6
Target Sequences: NM_000811 NP_000802.2 Q16445

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Proteins (2)
Recombinant (2)
GABRA6 (2)
No (2)
GST (1)
GST, N-terminus (1)
Human (2)
Wheat Germ Extract (2)
Purified (1)
GABRA6 Protein - 12.5% SDS-PAGE of human GABRA6 stained with Coomassie Blue
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Wheat Germ Extract
GST
77.4 kDa
2 µg/$439
GABRA6 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).