FSP27 / CIDEC

cell death-inducing DFFA-like effector c

Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. Its role in neutral lipid transfer and lipid droplet enlargement is activated by the interaction with PLIN1. May act as a CEBPB coactivator in the white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH. When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels, are quite resistant to apoptotic stimuli, the physiological significance of its role in apoptosis is unclear. May play a role in the modulation of the response to osmotic stress by preventing NFAT5 to translocate into the nucleus and activate its target genes expression.

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Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

FSP27 / CIDEC (8)

Publications

No (8)

Tag

GST (1)

GST, N-terminus (2)

GST, N-terminus + His, C-terminus (1)

His-T7 (2)

Myc-DDK (Flag) (2)

Species

Human (6)

Rat (1)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human FSP27 / CIDEC Protein (Recombinant GST) (Full Length) - LS-G34903

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

51.92 kDa

Price:

2 µg/$439

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Human FSP27 / CIDEC Protein (Recombinant GST, N-terminus + His, C-terminus) - LS-G144705

Source:

E. coli

Tag:

GST, N-terminus + His, C-terminus

Molecular Weight:

52.6 kDa

Price:

50 µg/$419

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Rat FSP27 / CIDEC Protein (Recombinant His-T7) (aa1-221) - LS-G26197

Source:

E. coli

Tag:

His-T7

Molecular Weight:

30.9 kDa

Price:

10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252

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Human FSP27 / CIDEC Protein (Recombinant GST, N-terminus) (aa53-141) - LS-G63059

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human FSP27 / CIDEC Protein (Recombinant GST, N-terminus) (aa1-238) - LS-G56861

Source:

E. coli

Tag:

GST, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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FSP27 / CIDEC Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101790

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.6 kDa

Price:

100 µg/$494

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Human FSP27 / CIDEC Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91581

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.6 kDa

Price:

20 µg/$150

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Human FSP27 / CIDEC Protein (Recombinant His-T7) (aa1-251) - LS-G16245

Source:

E. coli

Tag:

His-T7

Molecular Weight:

32.1 kDa

Price:

10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225

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