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Adapter protein that links FGF and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.
Gene Name: | fibroblast growth factor receptor substrate 3 |
Synonyms: | FRS3, FGFR substrate 3, FRS2-beta, FGFR-signaling adaptor SNT2, FRS2B, SNT-2, FRS2beta, SNT2 |
Target Sequences: | NM_006653 NP_006644.1 O43559 |
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