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FP / PTGFR

prostaglandin F receptor (FP)

Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum (By similarity). Isoforms 2 to 7 do not bind PGF2-alpha but are proposed to modulate signaling by participating in variant receptor complexes; heterodimers between isoform 1 and isoform 5 are proposed to be a receptor for prostamides including the synthetic analog bimatoprost.

Gene Name: prostaglandin F receptor (FP)
Family/Subfamily: GPCR , Prostanoid
Synonyms: PTGFR, PGF receptor, PGF2-alpha receptor, Prostaglandin F receptor (FP), FP, PGF2 alpha receptor, Prostaglandin F receptor, Prostanoid FP receptor
Target Sequences: NM_000959 NP_000950.1 P43088

Publications (1)

1
Effect of Sex Steroids and PGF2a on the Expression of Their Receptors and Decorin in Bovine Caruncular Epithelial Cells in Early-Mid Pregnancy. Monika Jamiol, Magdalena Sozoniuk, Jacek Wawrzykowski, Marta Kankofer. Molecules (Basel, Switzerland). 2022 November;27: [Full Text Article] [PubMed:36364246] [PMC:PMC9653824] Related Antibodies: LS-A1049.

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
FP / PTGFR (3)
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GST (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
FP / PTGFR Protein - 12.5% SDS-PAGE of human PTGFR stained with Coomassie Blue
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Wheat Germ Extract
GST
66.5 kDa
2 µg/$439
FP / PTGFR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
40.05 kDa
20 µg/$150
FP / PTGFR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
40.05 kDa
100 µg/$494
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).