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FOXP2

forkhead box P2

FOXP2 is a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.

Gene Name: forkhead box P2
Family/Subfamily: Transcription factor , not assigned-Transcription factor
Synonyms: FOXP2, CAG repeat protein 44, Forkhead box protein P2, Forkhead box P2, SPCH1, CAGH44, TNRC10
Target Sequences: NM_014491 NP_055306.1 O15409

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Products
Proteins (8)
Over-Expression Lysate (5)
Recombinant (3)
FOXP2 (8)
No (8)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (6)
Human (6)
293T Cells (3)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (1)
FOXP2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
69.9 kDa
100 µg/$710
FOXP2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
79.9 kDa
20 µg/$215
Select
293T Cells
Myc-DDK (Flag)
79.9 kDa
20 µg/$215
FOXP2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
69.9 kDa
20 µg/$215
FOXP2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
79.9 kDa
100 µg/$710
FOXP2 Protein - 12.5% SDS-PAGE of human FOXP2 stained with Coomassie Blue
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Wheat Germ Extract
GST
33.6 kDa
10 µg/$479; 25 µg/$670
FOXP2 Protein - Purified recombinant protein FOXP2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
79.7 kDa
20 µg/$1,107
FOXP2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Viewing 1-8 of 8 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).