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FOXP1 belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Name: | forkhead box P1 |
Family/Subfamily: | Transcription factor , not assigned-Transcription factor |
Synonyms: | FOXP1, 12CC4, Glutamine-rich factor 1, HFKH1B, HSPC215, Forkhead box P1, Forkhead box protein P1, QRF1 |
Target Sequences: | NM_032682 AAH05055.1 Q9H334 |
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