FOXO4 / AFX1

forkhead box O4

Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

FOXO4 / AFX1 (3)

Publications

No (3)

Tag

His, N-Terminal (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

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Human FOXO4 / AFX1 Protein (Recombinant His, N-Terminal) - LS-G144342

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

53.5 kDa

Price:

50 µg/$419

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Human FOXO4 / AFX1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78465

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.5 kDa

Price:

20 µg/$150

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FOXO4 / AFX1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100682

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.5 kDa

Price:

100 µg/$494

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