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FOXN3 / CHES1 is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms.
Gene Name: | forkhead box N3 |
Synonyms: | FOXN3, C14orf116, Checkpoint suppressor 1, CHES1, Forkhead box N3, Forkhead box protein N3, PRO1635 |
Target Sequences: | NM_005197 NP_005188.2 O00409 |
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