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FOXN1

forkhead box N1

Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia, resulting in a severely compromised immune system. This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression. A mutation in this gene has been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing in the 5' UTR of this gene has been observed.

Gene Name: forkhead box N1
Synonyms: FOXN1, FKHL20, Forkhead box protein N1, Forkhead box N1, WHN, Rowett nude, Winged helix nude, RONU, Winged-helix nude
Target Sequences: NM_003593 NP_003584.2 O15353

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
FOXN1 (3)
No (3)
GST (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
FOXN1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
68.7 kDa
100 µg/$710
FOXN1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
68.7 kDa
20 µg/$215
FOXN1 Protein - 12.5% SDS-PAGE of human FOXN1 stained with Coomassie Blue
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Wheat Germ Extract
GST
98.23 kDa
2 µg/$439
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).