FOS / c-FOS

FBJ murine osteosarcoma viral oncogene homolog

Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.

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Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

FOS / c-FOS (7)

Publications

No (7)

Tag

GST, N-terminus (2)

GST, N-terminus + His, C-terminus (1)

His, N-Terminal (2)

Myc-DDK (Flag) (2)

Species

Human (6)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human FOS / c-FOS Protein (Recombinant His, N-Terminal) (aa55-298) - LS-G13622

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

30.4 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human FOS / c-FOS Protein (Recombinant GST, N-terminus + His, C-terminus) - LS-G145202

Source:

E. coli

Tag:

GST, N-terminus + His, C-terminus

Molecular Weight:

68.5 kDa

Price:

50 µg/$419

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Human FOS / c-FOS Protein (Recombinant His, N-Terminal) - LS-G144059

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

40.5 kDa

Price:

50 µg/$419

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Human FOS / c-FOS Protein (Recombinant GST, N-terminus) (Full Length) - LS-G28511

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Molecular Weight:

67.54 kDa

Price:

10 µg/$479; 25 µg/$670

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Human FOS / c-FOS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75340

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.5 kDa

Price:

20 µg/$150

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Human FOS / c-FOS Protein (Recombinant GST, N-terminus) (aa1-100) - LS-G58600

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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FOS / c-FOS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100498

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.5 kDa

Price:

100 µg/$494

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