FLVCR / FLVCR1

feline leukemia virus subgroup C cellular receptor 1

Isoform 1: Heme transporter that exports cytoplasmic heme. It can also export coproporphyrin and protoporphyrin IX, which are both intermediate products in the heme biosynthetic pathway. Does not export bilirubin. Heme export depends on the presence of HPX and may be required to protect developing erythroid cells from heme toxicity. Heme export also provides protection from heme or ferrous iron toxicities in liver and brain. Causes susceptibility to FeLV-C in vitro. Required during erythtopoiesis to maintain intracellular free heme balance since in proerythroblasts, heme synthesis intensifies and it's accumulation is toxic for cells.Isoform 2: Heme transporter that promotes heme efflux from the mitochondrion to the cytoplasm. Essential for erythroid differentiation.

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

FLVCR / FLVCR1 (4)

Publications

No (4)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human FLVCR / FLVCR1 Protein (Recombinant GST) (Full Length) - LS-G33369

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

86.3 kDa

Price:

10 µg/$479; 25 µg/$670

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Human FLVCR / FLVCR1 Protein (Recombinant GST, N-terminus) (aa1-83) - LS-G62291

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human FLVCR / FLVCR1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89876

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.7 kDa

Price:

20 µg/$150

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FLVCR / FLVCR1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101157

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.7 kDa

Price:

100 µg/$494

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