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FLT3LG / Flt3 Ligand

fms-related tyrosine kinase 3 ligand

Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).

Gene Name:	fms-related tyrosine kinase 3 ligand
Synonyms:	FLT3LG, FL, Flt3 ligand, FLT3L, SL cytokine
Target Sequences:	NM_001459 NP_001450.2 P49771

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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