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May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling. Involved in early embryonic development (By similarity). May play a role in regulation of cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation.
Gene Name: | flightless I homolog (Drosophila) |
Synonyms: | FLII, FLI, FLIL, Protein flightless-1 homolog |
Target Sequences: | NM_002018 NP_002009.1 Q13045 |
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