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FKBP5 / FKBP51

FK506 binding protein 5

FKBP5 / FKBP51 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.

Gene Name: FK506 binding protein 5
Synonyms: FKBP5, 51 kd fk506-binding protein, 51 kDa FK506-binding protein, 51 kDa FK506-binding protein 5, 51 kDa FKBP, AIG6, Androgen-regulated protein 6, FKBP-51, FKBP-5, FKBP51, FF1 antigen, FK506 binding protein 5, p54, Ptg-10, Rotamase, T-cell FK506-binding protein, PPIase, PPIase FKBP5, FK506-binding protein 5, FKBP54, HSP90-binding immunophilin
Target Sequences: NM_004117 NP_004108.1 Q13451

Publications (1)

1
Regulation of Serine-Threonine Kinase Akt Activation by NAD+<sup>-Dependent Deacetylase SIRT7. Yu J, Qin B, Wu F, Qin S, Nowsheen S, Shan S, Zayas J, Pei H, Lou Z, Wang L. Cell reports. 2017 January;18:1229-1240. [Full Text Article] [PubMed:28147277] [PMC:PMC5298804]

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FKBP5 / FKBP51 (8)
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FKBP5 / FKBP51 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Saliva, Serum, Tissue Homogenates
1 Plate/$783
FKBP5 / FKBP51 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$834
FKBP5 / FKBP51 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
FKBP5 / FKBP51 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$854
FKBP5 / FKBP51 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
FKBP5 / FKBP51 ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
500 Wells/$1,247; 1000 Wells/$1,855
FKBP5 / FKBP51 ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
500 Wells/$1,276; 1000 Wells/$1,903
FKBP5 / FKBP51 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.2 - 50 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$672
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).