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FGG / Fibrinogen Gamma
fibrinogen gamma chain
Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.
| Gene Name: | fibrinogen gamma chain |
| Synonyms: | FGG, Fibrinogen gamma-b chain, Fibrinogen gamma chain, Fibrinogen, gamma polypeptide |
| Target Sequences: | NM_021870 NP_068656.2 P02679 |
Publications (2)
1
Compression force sensing regulates integrin aIIbß3adhesive function on diabetic platelets. Ju L, McFadyen JD, Al-Daher S, Alwis I, Chen Y, Tønnesen LL, Maiocchi S, Coulter B, Calkin AC, Felner EI, Cohen N, Yuan Y, Schoenwaelder SM, Cooper ME, Zhu C, Jackson SP. Nature communications. 2018 March;9:1087. (Human)
[Full Text Article]
[PubMed:29540687]
[PMC:PMC5852038]
Related Antibodies: LS-C418056.
2
A novel urinary biomarker protein panel to identify children with ureteropelvic junction obstruction - A pilot study. Charan Kumar V Devarakonda, Emily R Shearier, Chaoran Hu, James Grady, Jeremy L Balsbaugh, John H Makari, Fernando A Ferrer, Linda H Shapiro. Journal of pediatric urology. 2020 Aug;;16:466.e1-466.e9. [Full Text Article]
[PubMed:32620509]
[PMC:PMC7529974]
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FGG / Fibrinogen Gamma Mouse anti-Human Monoclonal (1F2) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
FGG / Fibrinogen Gamma Rabbit anti-Human Polyclonal (aa216-265) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
FGG / Fibrinogen Gamma Rabbit anti-Human Polyclonal (aa420-449) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
FGG / Fibrinogen Gamma Mouse anti-Human Monoclonal (aa166-416) Antibody
Human
WB
Unconjugated
100 µl/$314; 200 µl/$359; 500 µl/$507; 1 ml/$581
FGG / Fibrinogen Gamma Mouse anti-Human Monoclonal (aa166-416) (FITC) Antibody
Human
ICC, WB
FITC Conjugated
200 µl/$388
FGG / Fibrinogen Gamma Mouse anti-Human Monoclonal (4H9) Antibody
Mouse, Human
Flo, ICC, IF, IHC, WB
Unconjugated
100 µl/$541
FGG / Fibrinogen Gamma Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
FGG / Fibrinogen Gamma Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ICC, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
FGG / Fibrinogen Gamma Rabbit anti-Rat Polyclonal (aa170-429) Antibody
Rat
IHC, IHC-P, WB
Unconjugated
50 µl/$460
FGG / Fibrinogen Gamma Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
FGG / Fibrinogen Gamma Mouse anti-Human Monoclonal (OTI1F5) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
FGG / Fibrinogen Gamma Mouse anti-Human Monoclonal (4H9) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$459
FGG / Fibrinogen Gamma Mouse anti-Human Monoclonal (aa166-416) (Biotin) (IgG1,k) Antibody
Human
ICC, WB
Biotin Conjugated
200 µl/$373
FGG / Fibrinogen Gamma Mouse anti-Human Monoclonal (5A6) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µl/$459
FGG / Fibrinogen Gamma Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
FGG / Fibrinogen Gamma Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
FGG / Fibrinogen Gamma Rabbit anti-Human Polyclonal (aa417-445) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
FGG / Fibrinogen Gamma Rabbit anti-Human Polyclonal (aa301-350) (HRP) Antibody
Xenopus, Bat, Rat, Rabbit, Mouse, Dog, Guinea pig, Pig, Human, Monkey, Chimpanzee, Gibbon
WB
HRP Conjugated
100 µl/$442
FGG / Fibrinogen Gamma Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
FGG / Fibrinogen Gamma Rabbit anti-Human Polyclonal (aa166-416) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
FGG / Fibrinogen Gamma Sheep anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
200 µg/$658
FGG / Fibrinogen Gamma Mouse anti-Human Monoclonal (OTI1D11) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
FGG / Fibrinogen Gamma Mouse anti-Human Monoclonal (OTI2D2) Antibody
Mouse, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$434
FGG / Fibrinogen Gamma Rabbit anti-Human Polyclonal (aa91-118) Antibody
Mouse, Human
Flo, IF, WB
Unconjugated
400 µl/$393
FGG / Fibrinogen Gamma Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
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