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FGG / Fibrinogen Gamma

fibrinogen gamma chain

Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

Gene Name: fibrinogen gamma chain
Synonyms: FGG, Fibrinogen gamma-b chain, Fibrinogen gamma chain, Fibrinogen, gamma polypeptide
Target Sequences: NM_021870 NP_068656.2 P02679

Publications (2)

1
Compression force sensing regulates integrin aIIbß3adhesive function on diabetic platelets. Ju L, McFadyen JD, Al-Daher S, Alwis I, Chen Y, Tønnesen LL, Maiocchi S, Coulter B, Calkin AC, Felner EI, Cohen N, Yuan Y, Schoenwaelder SM, Cooper ME, Zhu C, Jackson SP. Nature communications. 2018 March;9:1087. (Human) [Full Text Article] [PubMed:29540687] [PMC:PMC5852038] Related Antibodies: LS-C418056.
2
A novel urinary biomarker protein panel to identify children with ureteropelvic junction obstruction - A pilot study. Charan Kumar V Devarakonda, Emily R Shearier, Chaoran Hu, James Grady, Jeremy L Balsbaugh, John H Makari, Fernando A Ferrer, Linda H Shapiro. Journal of pediatric urology. 2020 Aug;;16:466.e1-466.e9. [Full Text Article] [PubMed:32620509] [PMC:PMC7529974]

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FGG / Fibrinogen Gamma Antibody - Anti-FGG / Fibrinogen Gamma Chain antibody IHC of human intravascular plasma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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FGG / Fibrinogen Gamma Mouse anti-Human Monoclonal (1F2) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
FGG / Fibrinogen Gamma Antibody - Anti-FGG / Fibrinogen Gamma Chain antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FGG / Fibrinogen Gamma Rabbit anti-Human Polyclonal (aa216-265) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
FGG / Fibrinogen Gamma Antibody - FIBG Antibody IHC of formalin-fixed and paraffin-embedded human skeletal muscle tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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FGG / Fibrinogen Gamma Rabbit anti-Human Polyclonal (aa420-449) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
FGG / Fibrinogen Gamma Antibody - Western Blot ;Sample: Recombinant FGg, Human.
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FGG / Fibrinogen Gamma Mouse anti-Human Monoclonal (aa166-416) Antibody
Human
WB
Unconjugated
100 µl/$314; 200 µl/$359; 500 µl/$507; 1 ml/$581
FGG / Fibrinogen Gamma ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.469 - 30 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
FGG / Fibrinogen Gamma ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
FGG / Fibrinogen Gamma ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
FGG / Fibrinogen Gamma ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.625 - 1000 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$771
FGG / Fibrinogen Gamma ELISA Kit
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Sandwich
96-Well Strip Plate
Human
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$834
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FGG / Fibrinogen Gamma Mouse anti-Human Monoclonal (aa166-416) (FITC) Antibody
Human
ICC, WB
FITC Conjugated
200 µl/$388
FGG / Fibrinogen Gamma Antibody - Fibrinogen gamma Antibody in Immunohistochemistry (IHC)
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FGG / Fibrinogen Gamma Mouse anti-Human Monoclonal (4H9) Antibody
Mouse, Human
Flo, ICC, IF, IHC, WB
Unconjugated
100 µl/$541
FGG / Fibrinogen Gamma Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded cerebellum tissues with DAB staining using Fibrinogen gamma Monoclonal Antibody.
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FGG / Fibrinogen Gamma Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
FGG / Fibrinogen Gamma Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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FGG / Fibrinogen Gamma Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ICC, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
FGG / Fibrinogen Gamma Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FGG / Fibrinogen Gamma Rabbit anti-Rat Polyclonal (aa170-429) Antibody
Rat
IHC, IHC-P, WB
Unconjugated
50 µl/$460
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FGG / Fibrinogen Gamma Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
FGG / Fibrinogen Gamma Antibody - Immunofluorescent staining of HeLa cells using anti-FGG mouse monoclonal antibody.
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FGG / Fibrinogen Gamma Mouse anti-Human Monoclonal (OTI1F5) Antibody
Human
IF, WB
Unconjugated
100 µl/$434
FGG / Fibrinogen Gamma Antibody - IHC of paraffin-embedded cerebellum tissues using FGG mouse monoclonal antibody with DAB staining.
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FGG / Fibrinogen Gamma Mouse anti-Human Monoclonal (4H9) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$459
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FGG / Fibrinogen Gamma Mouse anti-Human Monoclonal (aa166-416) (Biotin) (IgG1,k) Antibody
Human
ICC, WB
Biotin Conjugated
200 µl/$373
FGG / Fibrinogen Gamma Antibody - Immunofluorescence of NIH/3T3 cells using FGG mouse monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
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FGG / Fibrinogen Gamma Mouse anti-Human Monoclonal (5A6) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µl/$459
FGG / Fibrinogen Gamma Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue at dilution of 1:100
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FGG / Fibrinogen Gamma Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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FGG / Fibrinogen Gamma Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
FGG / Fibrinogen Gamma Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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FGG / Fibrinogen Gamma Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
FGG / Fibrinogen Gamma Antibody - FGG Antibody (RB18714) IHC of formalin-fixed and paraffin-embedded human hepatocarcinoma tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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FGG / Fibrinogen Gamma Rabbit anti-Human Polyclonal (aa417-445) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
FGG / Fibrinogen Gamma Antibody - FGG antibody ARP44300_T100-NP_000500-FGG(fibrinogen gamma chain) Antibody Western blot of Fetal Liver lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FGG / Fibrinogen Gamma Rabbit anti-Human Polyclonal (aa301-350) (HRP) Antibody
Xenopus, Bat, Rat, Rabbit, Mouse, Dog, Guinea pig, Pig, Human, Monkey, Chimpanzee, Gibbon
WB
HRP Conjugated
100 µl/$442
FGG / Fibrinogen Gamma Antibody - Western blot of recombinant FGG / Fibrinogen Gamma.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FGG / Fibrinogen Gamma Rabbit anti-Human Polyclonal (aa166-416) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
Viewing 1-25 of 140 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).