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Unfortunately, the antibody (ID:196904) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



FGFR3

fibroblast growth factor receptor 3

Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts. Promotes apoptosis in chondrocytes, but can also promote cancer cell proliferation. Required for normal development of the inner ear. Phosphorylates PLCG1, CBL and FRS2. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Plays a role in the regulation of vitamin D metabolism. Mutations that lead to constitutive kinase activation or impair normal FGFR3 maturation, internalization and degradation lead to aberrant signaling. Over-expressed or constitutively activated FGFR3 promotes activation of PTPN11/SHP2, STAT1, STAT5A and STAT5B. Secreted isoform 3 retains its capacity to bind FGF1 and FGF2 and hence may interfere with FGF signaling.

Gene Name: fibroblast growth factor receptor 3
Family/Subfamily: Protein Kinase , FGF Receptor
Synonyms: FGFR3, CD333, CD333 antigen, ACH, FGF receptor 3, HSFGFR3EX, Hydroxyaryl-protein kinase, JTK4, FGFR-3, CEK2, Tyrosine kinase JTK4
Target Sequences: NM_000142 NP_000133.1 P22607

Filtered By: None
Target
fgfr3 (46)
Reactivity
Human (41)
Mouse (20)
Rat (9)
Bovine (1)
Cynomolgus (1)
Dog (1)
Pig (1)
Application
IHC (22)
IHC-P (9)
WB (38)
ELISA (26)
ICC (2)
IF (1)
IP (2)
Host
rabbit (43)
mouse (3)
Isotype
IgG (29)
IgG1 (2)
IgG2a (1)
Clonality
monoclonal mc (3)
polyclonal pc (43)
Clone
136312 (1)
1B10 (1)
1G10 (1)
Format
AP Conjugated (2)
APC Conjugated (2)
Azide-free (2)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (29)
Epitope
aa468-495 (7)
aa777-806 (7)
aa166-375 (3)
C-Terminus (2)
Internal (1)
N-Terminus (1)
Trp153 (1)
aa100-180 (1)
aa110-129 (1)
aa131-180 (1)
aa23-375 (1)
aa359-372 (1)
aa449-482 (1)
aa467-495 (1)
aa776-806 (1)
Publications
No (46)
Showing 1-25 out of 46 results
Anti-FGFR3 Antibody (aa359-372) IHC-plus™ LS-B2684

Rabbit Polyclonal (IgG) to Human FGFR3
Human
IHC-P
Unconjugated
Anti-FGFR3 Antibody (C-Terminus) LS-C201110

Rabbit Polyclonal to Human FGFR3
Mouse, Rat, Human
ELISA IF IHC WB
Unconjugated
Anti-FGFR3 Antibody (clone 136312) LS-C149945

Mouse Monoclonal [clone 136312] (IgG1) to Human FGFR3
Human
ICC IHC-P WB
Unconjugated
Anti-FGFR3 Antibody (N-Terminus) LS-C66140

Rabbit Polyclonal (IgG) to Human FGFR3
Human
IHC-P IP WB
Unconjugated
Anti-FGFR3 Antibody (C-Terminus) LS-C66139

Rabbit Polyclonal (IgG) to Human FGFR3
Human
IHC-P IP WB
Unconjugated
Anti-FGFR3 Antibody (aa131-180) LS-C118448

Rabbit Polyclonal (IgG) to Human FGFR3
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
Anti-FGFR3 Antibody (aa776-806) LS-C97523

Rabbit Polyclonal to Human FGFR3
IHC WB
Unconjugated
Anti-FGFR3 Antibody (aa110-129) LS-C313253

Rabbit Polyclonal (IgG) to Human FGFR3
Rat, Human
ICC IHC-P WB
Unconjugated
Anti-FGFR3 Antibody (aa467-495) LS-C321382

Rabbit Polyclonal (IgG) to Mouse FGFR3
Mouse, Human
ELISA IHC WB
Unconjugated
Anti-FGFR3 Antibody (aa468-495, Biotin) LS-C214235

Rabbit Polyclonal (IgG) to Mouse FGFR3
Mouse, Human
ELISA IHC WB
Biotin Conjugated
Anti-FGFR3 Antibody (aa468-495, FITC) LS-C214236

Rabbit Polyclonal (IgG) to Mouse FGFR3
Mouse, Human
ELISA IHC WB
FITC Conjugated
Anti-FGFR3 Antibody (aa468-495, Azide-free, HRP) LS-C214248

Rabbit Polyclonal (IgG) to Mouse FGFR3
Mouse, Human
ELISA IHC WB
HRP Conjugated, Azide-free
Anti-FGFR3 Antibody (aa468-495, AP) LS-C214233

Rabbit Polyclonal (IgG) to Mouse FGFR3
Mouse, Human
ELISA IHC WB
AP Conjugated
Anti-FGFR3 Antibody (aa468-495, PE) LS-C214237

Rabbit Polyclonal (IgG) to Mouse FGFR3
Mouse, Human
ELISA IHC WB
PE Conjugated
Anti-FGFR3 Antibody (aa468-495, APC) LS-C214250

Rabbit Polyclonal (IgG) to Mouse FGFR3
Mouse, Human
ELISA IHC WB
APC Conjugated
Anti-FGFR3 Antibody (aa166-375) LS-C293910

Rabbit Polyclonal (IgG) to Human FGFR3
Human
ELISA WB
Unconjugated
Anti-FGFR3 Antibody (aa468-495) LS-C164387

Rabbit Polyclonal to Mouse FGFR3
Mouse, Human
IHC-P WB
Unconjugated
Anti-FGFR3 Antibody (aa23-375, clone 1B10) LS-C336304

Mouse Monoclonal [clone 1B10] (IgG1) to Human FGFR3
Human
IHC-P WB
Unconjugated
Anti-FGFR3 Antibody (clone 1G10) LS-C175535

Mouse Monoclonal [clone 1G10] (IgG2a) to Human FGFR3
Human
WB
Unconjugated
Anti-FGFR3 Antibody (aa777-806) LS-C327389

Rabbit Polyclonal (IgG) to Human FGFR3
Human
ELISA IHC WB
Unconjugated
Anti-FGFR3 Antibody (aa777-806, APC) LS-C219330

Rabbit Polyclonal (IgG) to Human FGFR3
Human
ELISA IHC WB
APC Conjugated
Anti-FGFR3 Antibody (aa777-806, AP) LS-C219326

Rabbit Polyclonal (IgG) to Human FGFR3
Human
ELISA IHC WB
AP Conjugated
Anti-FGFR3 Antibody (aa777-806, Azide-free, HRP) LS-C219333

Rabbit Polyclonal (IgG) to Human FGFR3
Human
ELISA IHC WB
HRP Conjugated, Azide-free
Anti-FGFR3 Antibody LS-C415118

Rabbit Polyclonal to Human FGFR3
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
Anti-FGFR3 Antibody (aa100-180) LS-C383487

Rabbit Polyclonal (IgG) to Human FGFR3
Mouse, Rat, Human
ELISA IHC WB
Unconjugated

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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