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Unfortunately, the antibody (ID:151881) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



FGFR1 / FGF Receptor 1

fibroblast growth factor receptor 1

Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes phosphorylation of SHC1, STAT1 and PTPN11/SHP2. In the nucleus, enhances RPS6KA1 and CREB1 activity and contributes to the regulation of transcription. FGFR1 signaling is down-regulated by IL17RD/SEF, and by FGFR1 ubiquitination, internalization and degradation.

Gene Name: fibroblast growth factor receptor 1
Family/Subfamily: Protein Kinase , FGF Receptor
Synonyms: FGFR1, BFGF receptor, BFGF-R, BFGF-R-1, CD331, Cek1, CD331 antigen, FGFR1/PLAG1 fusion, FLT2, Fgf-flg, FGFBR, FGFR-1, Fms-like tyrosine kinase 2, HBGFR, HH2, Hydroxyaryl-protein kinase, FGF receptor 1, Fms-related tyrosine kinase 2, Proto-oncogene c-Fgr, BFGFR, CEK, FLT-2, HBGF receptor, KAL2, OGD
Target Sequences: NM_023110 CAA47375.1 P11362

Publications (2)

1
PDGF, TGF-beta, and FGF signaling is important for differentiation and growth of mesenchymal stem cells (MSCs): transcriptional profiling can identify markers and signaling pathways important in differentiation of MSCs into adipogenic, chondrogenic, and o. Ng F, Boucher S, Koh S, Sastry KS, Chase L, Lakshmipathy U, Choong C, Yang Z, Vemuri MC, Rao MS, Tanavde V. Blood. 2008 112:295-307. [PubMed:18332228] Related Antibodies: LS-C96873.
2
Ureteral obstruction promotes proliferation and differentiation of the renal urothelium into a bladder-like phenotype. Girshovich A, Vinsonneau C, Perez J, Vandermeersch S, Verpont MC, Placier S, Jouanneau C, Letavernier E, Baud L, Haymann JP. Kidney international. 2012 82:428-35. [PubMed:22513823] Related Antibodies: LS-C96872.

Filtered By: None
Target
fgfr1-fgf-receptor-1 (187)
Reactivity
Human (180)
Mouse (89)
Rat (64)
Bat (2)
Bovine (21)
Chicken (19)
Dog (3)
Guinea pig (9)
Horse (4)
Monkey (4)
Opossum (1)
Pig (6)
Rabbit (6)
Zebrafish (2)
Application
IHC (45)
IHC-Fr (3)
IHC-P (20)
WB (171)
Flo (11)
DB (8)
ELISA (112)
FLISA (1)
ICC (8)
IF (18)
IP (34)
Host
rabbit (148)
mouse (37)
goat (2)
Isotype
IgG (105)
IgG1 (16)
IgG1,k (1)
IgG2a (2)
IgG2a,k (1)
IgG2b (5)
IgM (8)
Clonality
monoclonal mc (37)
polyclonal pc (150)
Clone
1440CT772.50.23 (1)
1A3 (1)
3C4 (1)
3D4F7 (1)
5D5 (1)
5E9 (1)
6F8 (1)
GF1 (1)
M 1 C4 (1)
M 17A3 (1)
M17D10 (1)
M19B2 (1)
M2F12 (1)
M5G 10 (1)
VBS1 (1)
VBS-7 (2)
Format
AP Conjugated (12)
APC Conjugated (12)
Azide-free (10)
Biotin Conjugated (17)
FITC Conjugated (17)
HRP Conjugated (14)
PE Conjugated (12)
Unconjugated (103)
Epitope
N-Terminus (16)
pTyr766 (15)
Tyr154 (8)
Tyr463 (8)
Tyr653 (8)
Tyr766 (8)
Tyr307 (7)
aa756-784 (7)
aa236-362 (6)
pTyr154 (6)
pTyr654 (6)
aa1-376 (4)
aa112-161 (4)
aa22-376 (4)
C-Terminus (3)
pTyr307 (2)
pTyr653/Tyr654 (2)
Arg148 (1)
Glu160 (1)
Ile648 (1)
Leu760 (1)
aa121-170 (1)
aa152-156 (1)
aa19-48 (1)
aa23-325 (1)
aa285-314 (1)
aa291-324 (1)
aa360-373 (1)
aa600-680 (1)
aa626-675 (1)
aa710-790 (1)
aa736-785 (1)
aa755-784 (1)
aa806-842 (1)
aa837-852 (1)
aa87-98 (1)
aa90-170 (1)
pTyr653 (1)
pTyr653/654 (1)
Publications
No (185)
Yes (2)
Showing 1-25 out of 187 results
Anti-FGFR1 / FGF Receptor 1 Antibody (N-Terminus, clone M19B2) IHC-plus™ LS-B6250

Mouse Monoclonal [clone M19B2] (IgG1) to Human FGFR1 / FGF Receptor 1
Human
IHC-P IP WB
Unconjugated
Anti-FGFR1 / FGF Receptor 1 Antibody (phospho-Tyr653/Tyr654) LS-C96872

Rabbit Polyclonal to Human FGFR1 / FGF Receptor 1
Mouse, Human
IHC-P WB
Unconjugated
Anti-FGFR1 / FGF Receptor 1 Antibody (aa837-852) IHC-plus™ LS-B3031

Goat Polyclonal to Human FGFR1 / FGF Receptor 1
Dog, Bovine, Horse, Bat, Human, Monkey
ELISA IHC-P WB
Unconjugated
Anti-FGFR1 / FGF Receptor 1 Antibody (clone VBS-7) LS-C23660

Mouse Monoclonal [clone VBS-7] (IgG1) to Bovine FGFR1 / FGF Receptor 1
Chicken, Bovine, Mouse, Guinea pig, Rat, Human
ELISA IHC-Fr IP WB
Unconjugated
Anti-FGFR1 / FGF Receptor 1 Antibody (N-Terminus) LS-C66134

Mouse Monoclonal (IgG1) to Human FGFR1 / FGF Receptor 1
Human
Flo IP WB
Unconjugated
Anti-FGFR1 / FGF Receptor 1 Antibody (aa736-785) LS-C117645

Rabbit Polyclonal (IgG) to Human FGFR1 / FGF Receptor 1
Mouse, Rat, Human
ELISA IHC-P WB
Unconjugated
Anti-FGFR1 / FGF Receptor 1 Antibody (N-Terminus, clone M2F12) IHC-plus™ LS-B6232

Mouse Monoclonal [clone M2F12] (IgG2a) to Human FGFR1 / FGF Receptor 1
Mouse, Rat, Human
IHC-P IP WB
Unconjugated
Anti-FGFR1 / FGF Receptor 1 Antibody (N-Terminus, clone M 17A3) IHC-plus™ LS-B6233

Mouse Monoclonal [clone M 17A3] (IgG2b) to Human FGFR1 / FGF Receptor 1
Human
IHC-P IP WB
Unconjugated
Anti-FGFR1 / FGF Receptor 1 Antibody (N-Terminus) IHC-plus™ LS-B6329

Mouse Monoclonal (IgG2a) to Human FGFR1 / FGF Receptor 1
Mouse, Rat, Human
IHC-Fr IHC-P IP WB
Unconjugated
Anti-FGFR1 / FGF Receptor 1 Antibody LS-C166142

Rabbit Polyclonal to Human FGFR1 / FGF Receptor 1
Human
Flo IHC-P WB
Unconjugated
Anti-FGFR1 / FGF Receptor 1 Antibody (N-Terminus, Biotin) LS-C257263

Rabbit Polyclonal (IgG) to Human FGFR1 / FGF Receptor 1
Mouse, Human
ELISA Flo ICC IF IHC IP WB
Biotin Conjugated
Anti-FGFR1 / FGF Receptor 1 Antibody (N-Terminus, FITC) LS-C257262

Rabbit Polyclonal (IgG) to Human FGFR1 / FGF Receptor 1
Mouse, Human
FLISA Flo IF IHC WB
FITC Conjugated
Anti-FGFR1 / FGF Receptor 1 Antibody (N-Terminus, AP) LS-C257260

Rabbit Polyclonal (IgG) to Human FGFR1 / FGF Receptor 1
Mouse, Human
ELISA Flo ICC IF IHC IP WB
AP Conjugated
Anti-FGFR1 / FGF Receptor 1 Antibody (N-Terminus, APC) LS-C257261

Rabbit Polyclonal (IgG) to Human FGFR1 / FGF Receptor 1
Mouse, Human
ELISA Flo ICC IF IHC IP WB
APC Conjugated
Anti-FGFR1 / FGF Receptor 1 Antibody (N-Terminus, Azide-free, HRP) LS-C257268

Rabbit Polyclonal (IgG) to Human FGFR1 / FGF Receptor 1
Mouse, Human
ELISA Flo ICC IF IHC IP WB
HRP Conjugated, Azide-free
Anti-FGFR1 / FGF Receptor 1 Antibody (phospho-Tyr766) LS-C96873

Rabbit Polyclonal to Human FGFR1 / FGF Receptor 1
Human
IHC-P WB
Unconjugated
Anti-FGFR1 / FGF Receptor 1 Antibody LS-C121820

Mouse Monoclonal (IgM) to Human FGFR1 / FGF Receptor 1
Chicken, Bovine, Mouse, Rat, Human
ELISA IP WB
Unconjugated
Anti-FGFR1 / FGF Receptor 1 Antibody (N-Terminus, clone M17D10) IHC-plus™ LS-B6251

Mouse Monoclonal [clone M17D10] (IgG1) to Human FGFR1 / FGF Receptor 1
Human
IHC-P IP WB
Unconjugated
Anti-FGFR1 / FGF Receptor 1 Antibody (aa23-325) LS-C23658

Mouse Monoclonal (IgG1) to Human FGFR1 / FGF Receptor 1
Rat, Human
IP WB
Unconjugated
Anti-FGFR1 / FGF Receptor 1 Antibody (aa360-373) LS-C33228

Rabbit Polyclonal to Human FGFR1 / FGF Receptor 1
Human
IHC-P
Unconjugated
Anti-FGFR1 / FGF Receptor 1 Antibody (N-Terminus) LS-C97512

Rabbit Polyclonal to Human FGFR1 / FGF Receptor 1
Mouse, Human
Flo IF IP WB
Unconjugated
Anti-FGFR1 / FGF Receptor 1 Antibody (aa626-675) LS-C117646

Rabbit Polyclonal (IgG) to Human FGFR1 / FGF Receptor 1
Mouse, Rat, Human
ELISA IF WB
Unconjugated
Anti-FGFR1 / FGF Receptor 1 Antibody (clone M 1 C4) LS-C83406

Mouse Monoclonal [clone M 1 C4] (IgG1) to Human FGFR1 / FGF Receptor 1
Human
IP WB
Unconjugated
Anti-FGFR1 / FGF Receptor 1 Antibody (N-Terminus, clone M5G 10) LS-C83403

Mouse Monoclonal [clone M5G 10] (IgG1) to Human FGFR1 / FGF Receptor 1
Human
IP WB
Unconjugated
Anti-FGFR1 / FGF Receptor 1 Antibody (N-Terminus, Azide-free) LS-C66129

Rabbit Polyclonal (IgG) to Human FGFR1 / FGF Receptor 1
Human
IP WB
Unconjugated, Azide-free

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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