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FGF4

fibroblast growth factor 4

FGF4 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.

Gene Name: fibroblast growth factor 4
Family/Subfamily: HBGF , not assigned-HBGF
Synonyms: FGF4, Fibroblast growth factor 4, FGF-4, Hst, HSTF-1, Kaposi sarcoma oncogene, K-FGF, KFGF, HBGF-4, HST-1, Oncogene HST, HSTF1, KS3, Transforming protein KS3
Target Sequences: NM_002007 NP_001998.1 P08620

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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).