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FGF21
fibroblast growth factor 21
Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB.
| Gene Name: | fibroblast growth factor 21 |
| Family/Subfamily: | HBGF , not assigned-HBGF |
| Synonyms: | FGF21, Fibroblast growth factor 21, FGF-21 |
| Target Sequences: | NM_019113 NP_061986.1 Q9NSA1 |
Publications (4)
1
Deficiency in interleukin-18 promotes differentiation of brown adipose tissue resulting in fat accumulation despite dyslipidemia. Yamanishi K, Maeda S, Kuwahara-Otani S, Hashimoto T, Ikubo K, Mukai K, Nakasho K, Gamachi N, El-Darawish Y, Li W, Okuzaki D, Watanabe Y, Yamanishi H, Okamura H, Matsunaga H. Journal of translational medicine. 2018 November;16:314. [Full Text Article]
[PubMed:30453990]
[PMC:PMC6245626]
Related Antibodies: LS-B5864.
2
Relationship of HIV Status and Fatigue, Cardiorespiratory Fitness, Myokines, and Physical Activity. Allison R Webel, Trevor Jenkins, Christopher T Longenecker, Marianne Vest, Christine Horvat Davey, Jackson Currie, Rebecca Darrah, Paul Litman, Vitor Hugo Fernando de Oliveira, Richard A Josephson. The journal of the Association of Nurses in AIDS Care : JANAC. 2019 June;30:392-404. [Full Text Article]
[PubMed:31241504]
[PMC:PMC7179736]
3
Reversal of obesity-induced hypertriglyceridemia by (R)- alpha -lipoic acid in ZDF (fa/fa) rats. Yi X, Pashaj A, Xia M, Moreau R. Biochemical and biophysical research communications. 2013 Sep;439:390-5. [Full Text Article]
[PubMed:23994635]
Related Antibodies: LS-B5864.
☰ Filters
Products
Proteins
(35)
Type
Over-Expression Cell Culture Supernatant
(1)
Over-Expression Lysate
(3)
Recombinant
(31)
Target
FGF21
(35)
Format
Animal-free
(1)
Publications
No
(35)
Tag
6His, C-terminus
(2)
6His, N-terminus
(6)
DDK (Flag)
(1)
DDK,N-terminus
(1)
GST
(1)
His
(5)
His, C-Terminal
(1)
His, N-Terminal
(2)
His,C-terminus
(1)
His-GST, N-terminus
(1)
His-S
(1)
His-T7
(2)
Human IgG Fc
(1)
Human IgG1 Fc
(1)
Myc-DDK (Flag)
(3)
Species
Crab-eating macaque
(1)
Human
(18)
Mouse
(11)
Pig
(1)
Rat
(2)
Source
293T Cells
(1)
CHO Cells
(1)
E. coli
(20)
HEK 293 Cells
(9)
Human
(1)
Human Cells
(1)
Mammalian Cells
(1)
Wheat Germ Extract
(1)
Purification
Purified
(13)
Low Endotoxin Level
Low endotoxin level
(16)
Biologically Active
Biologically active
(6)
Animal-free
Animal-free
(1)
HEK 293 Cells
DDK,N-terminus
Less than 0.06 EU/µg protein (determined by LAL method).
~23 kDa (SDS-PAGE)
10 µg/$344; 50 µg/$519
E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
21.7 kDa
20 µg/$360; 100 µg/$728
Wheat Germ Extract
GST
45.54 kDa
10 µg/$479; 25 µg/$670
293T Cells
Myc-DDK (Flag)
19.4 kDa
20 µg/$150
HEK 293 Cells
Myc-DDK (Flag)
19.4 kDa
100 µg/$494
Human
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
20.8 kDa
10 µg/$335; 50 µg/$615
E. coli
His
24.03 kD
100 µg/$500; 20 µg/$364; 1 mg/$1,679
E. coli
His-T7
23.2 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
E. coli
His-S
23.56 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
E. coli
His
23.5 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
HEK 293 Cells
6His, N-terminus
22 kDa
100 µg/$298
E. coli
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
19.5 kDa (SDS-PAGE)
50 µg/$364; 10 µg/$278; 1 mg/$1,933
HEK 293 Cells
6His, N-terminus
22 kDa
200 µl/$283
E. coli
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
19.9 kDa (SDS-PAGE)
50 µg/$364; 10 µg/$278; 1 mg/$1,933
E. coli
6His, N-terminus
21.7 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365; 200 µg/$484
E. coli
6His, N-terminus
21 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
HEK 293 Cells
Myc-DDK (Flag)
19.4 kDa
20 µg/$1,107
HEK 293 Cells
Human IgG Fc
Less than 0.1 EU/µg protein (determined by LAL method).
~50kDa (SDS-PAGE)
50 µg/$463; 10 µg/$330
E. coli
None
Biologically active
19.4 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
E. coli
His
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
500 µg/$526; 100 µg/$316
E. coli
None
Less than 0.1 ng/µg of protein (less than 1EU/µg).
19.5 kDa
5 µg/$268; 25 µg/$349
E. coli
None
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
5 µg/$282; 25 µg/$370
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
20.2kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
HEK 293 Cells
His, N-Terminal
22 kDa
10 µg/$289; 200 µg/$646; 50 µg/$360
Viewing 1-25
of 35
product results
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