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FGF2 / Basic FGF

fibroblast growth factor 2 (basic)

FGF2 / Basic FGF is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

Gene Name: fibroblast growth factor 2 (basic)
Family/Subfamily: HBGF , not assigned-HBGF
Synonyms: FGF2, Basic fibroblast growth factor, FGFB, Fibroblast growth factor 2, FGF-2, Prostatropin, BFGF, HBGF-2
Target Sequences: NM_002006 NP_001997.5 P09038

Publications (1)

1
A phase Ib study of GSK3052230, an FGF ligand trap in combination with pemetrexed and cisplatin in patients with malignant pleural mesothelioma10<sup> Washington University School of Medicine, St. Louis, MO, USA12<sup> Memorial Sloan Kettering Cancer Center, New York, NY, USA14<sup> GlaxoSmithKline, Inc., 1250 South Collegeville Road, Collegeville, PA, USA16<sup> Utrecht University, Utrecht, The Netherlands18<sup> Phase I Trials Unit, Medical Oncology Department, Hospital Universitario Virgen de. Emilie M J van Brummelen, Evgeny Levchenko, Manuel Dómine, Dean A Fennell, Hedy L Kindler, Santiago Viteri, Shirish Gadgeel, Pilar Garrido López, Vladimir Kostorov, Daniel Morgensztern, Sergey Orlov, Marjorie G Zauderer, Johan F Vansteenkiste, Katherine Baker-Neblett, James Vasquez, Xiaowei Wang, David I Bellovin, Jan H M Schellens, Li Yan, Ionel Mitrica, M Phillip DeYoung, José Trigo. Investigational new drugs. 2020 Apr;;38:457-467. [Full Text Article] [PubMed:31065954] [PMC:PMC6898757] Related Antibodies: LS-B10042.

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Products
ELISA Kits (49)
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FGF2 / Basic FGF (49)
Human (14)
Mouse (8)
Rat (9)
Bovine (2)
Chicken (4)
Guinea pig (1)
Monkey (1)
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12 x 8-Well Microstrips (4)
96-Well Microplate (10)
96-Well Strip Plate (32)
Antibody Pair and Standard (1)
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Cell Culture Supernatants (18)
Cell Lysates (12)
Cell Supernatant (1)
EDTA Plasma (1)
Heparin Plasma (1)
Plasma (44)
Serum (45)
Tissue Homogenates (21)
FGF2 / Basic FGF ELISA Kit
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Sandwich
96-Well Microplate
Pig
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
FGF2 / Basic FGF ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
12.35 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$782
FGF2 / Basic FGF ELISA Kit
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Sandwich
96-Well Strip Plate
Sheep
6.25 - 400 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$911
FGF2 / Basic FGF ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
FGF2 / Basic FGF ELISA Kit
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Sandwich
12 x 8-Well Microstrips
Human
63 - 400 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$479
FGF2 / Basic FGF ELISA Kit
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Sandwich
96-Well Strip Plate
Human
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
FGF2 / Basic FGF ELISA Kit
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Sandwich
96-Well Strip Plate
Guinea pig
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
FGF2 / Basic FGF ELISA Kit
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Sandwich
96-Well Microplate
Bovine
4.1 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$672
FGF2 / Basic FGF ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
FGF2 / Basic FGF ELISA Kit
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Sandwich
96-Well Strip Plate
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
FGF2 / Basic FGF ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
4.7 - 300 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$1,100
FGF2 / Basic FGF ELISA Kit
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Competitive EIA
96-Well Strip Plate
Human
12.35 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$573
FGF2 / Basic FGF ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Pig
12.35 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$889
FGF2 / Basic FGF ELISA Kit
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Sandwich
96-Well Microplate
Human
102.4 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
FGF2 / Basic FGF ELISA Kit
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Sandwich
96-Well Microplate
Mouse
18.8 - 600 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
FGF2 / Basic FGF ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
FGF2 / Basic FGF ELISA Kit
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Development Kit
Antibody Pair and Standard
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$1,153; 1000 Wells/$1,698
FGF2 / Basic FGF ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
FGF2 / Basic FGF ELISA Kit
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Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$929
FGF2 / Basic FGF ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Rat
7.813 - 500 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
FGF2 / Basic FGF ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
12.5 - 800 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
FGF2 / Basic FGF ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
7.813 - 500 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
FGF2 / Basic FGF ELISA Kit
Select
Development Kit
1000 Wells
Human
63 - 4000 pg/ml
Colorimetric - 405nm (ABTS)
1 Test/$540
FGF2 / Basic FGF ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
FGF2 / Basic FGF ELISA Kit
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Sandwich
96-Well Microplate
Chicken
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).