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Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
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Additional Contact Details
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FEV / PET1
FEV (ETS oncogene family)
FEV / PET1 belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations.
| Gene Name: | FEV (ETS oncogene family) |
| Synonyms: | FEV, Fifth Ewing variant protein, HSRNAFEV, PET-1, PC12 ETS factor 1, Protein FEV, FEV (ETS oncogene family), FEV (fifth Ewing variant), PET1 |
| Target Sequences: | NM_017521 NP_059991.1 Q99581 |
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