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FCN3 / Ficolin-3

ficolin (collagen/fibrinogen domain containing) 3

Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified.

Gene Name: ficolin (collagen/fibrinogen domain containing) 3
Synonyms: FCN3, FCNH, Ficolin-3, HAKA1, Ficolin 3, H-ficolin, Hakata antigen
Target Sequences: NM_003665 NP_003656.2 O75636

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Proteins (6)
Over-Expression Lysate (4)
Recombinant (2)
FCN3 / Ficolin-3 (6)
No (6)
GST (1)
His, N-Terminal (1)
Myc-DDK (Flag) (4)
Human (4)
293T Cells (2)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (2)
FCN3 / Ficolin-3 Protein - Recombinant Ficolin 3 By SDS-PAGE
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E. coli
His, N-Terminal
30.2 kDa
10 µg/$260; 50 µg/$335; 100 µg/$497; 200 µg/$622; 1 mg/$1,588; 500 µg/$1,185; 5 mg/$2,522; 2 mg/$1,760
FCN3 / Ficolin-3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
32.9 kDa
20 µg/$150
FCN3 / Ficolin-3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
29.3 kDa
20 µg/$150
FCN3 / Ficolin-3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
32.9 kDa
100 µg/$494
FCN3 / Ficolin-3 Protein - 12.5% SDS-PAGE of human FCN3 stained with Coomassie Blue
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Wheat Germ Extract
GST
57.42 kDa
10 µg/$479; 25 µg/$670
FCN3 / Ficolin-3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
29.3 kDa
100 µg/$494
Viewing 1-6 of 6 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).