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Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Gene Name: | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) |
Synonyms: | FCGR3B, CD16b, CD16b antigen, CD16, Fc-gamma RIIIb, FCR-10, FCRIII, Fc-gamma RIII, Fc-gamma RIII-beta, FCG3, IGFR3, Fc-gamma receptor IIIb (CD 16), FCGR3, FCRIIIb, Igg fc receptor iii-1 |
Target Sequences: | NM_000570 NP_000561.3 O75015 |
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