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FcERI / Fc Epsilon RI

Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide

Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.

Gene Name: Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
Family/Subfamily: Immunoglobulin , not assigned-Immunoglobulin
Synonyms: FCER1A, Alpha polypeptide, FCE1A, FcERI, Fc Epsilon RI, Fc epsilon RI alpha-chain, Fc-epsilon RI-alpha, IgE Fc receptor subunit alpha
Target Sequences: NM_002001 NP_001992.1 P12319

Publications (1)

1
Characterization of Mast Cells from Healthy and Varicose Human Saphenous Vein. Katrine T Callesen, Sofia Mogren, Frida Berlin, Cecilia Andersson, Susanne Schmidt, Lotte Klitfod, Vanesa Esteban, Lars K Poulsen, Bettina M Jensen. Biomedicines. 2022 May;10: [Full Text Article] [PubMed:35625799] [PMC:PMC9138295] Related Antibodies: LS-B4054.

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Products
Proteins (9)
Over-Expression Lysate (2)
Recombinant (7)
FcERI / Fc Epsilon RI (9)
No (9)
10His-SUMO, N-terminus (1)
6His, N-terminus (1)
6His-SUMO, N-terminus (1)
GST, N-terminus (1)
His (1)
His, C-terminus (1)
Human IgG1 Fc (1)
Myc-DDK (Flag) (2)
Human (6)
Mouse (2)
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Human Cells (1)
Wheat Germ Extract (1)
Yeast (1)
Purified (6)
Low endotoxin level (2)
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HEK 293 Cells
Human IgG1 Fc
Less than 1.0 EU/µg protein (determined by LAL method).
48 kDa
100 µg/$721; 1 mg/$4,701
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Human Cells
His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
24.5 kDa
100 µg/$721; 1 mg/$4,701
FcERI / Fc Epsilon RI Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His-SUMO, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
FcERI / Fc Epsilon RI Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Yeast
6His, N-terminus
100 µg/$446; 20 µg/$336; 1 mg/$1,460
FcERI / Fc Epsilon RI Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
29.57 kDa
100 µg/$494
FcERI / Fc Epsilon RI Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
FcERI / Fc Epsilon RI Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
10His-SUMO, N-terminus
100 µg/$1,801; 20 µg/$1,247
FcERI / Fc Epsilon RI Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
29.57 kDa
20 µg/$150
FcERI / Fc Epsilon RI Protein - 12.5% SDS-PAGE of human FCER1A stained with Coomassie Blue
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Wheat Germ Extract
GST, N-terminus
54.01 kDa
10 µg/$479; 25 µg/$670
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).