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Members of the F-box protein family, such as FBXW9, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
Gene Name: | F-box and WD repeat domain containing 9 |
Family/Subfamily: | F-Box |
Synonyms: | FBXW9, Fbw9 |
Target Sequences: | NM_032301 NP_115677.2 Q5XUX1 |
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