FBXO2

F-box protein 2

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type.

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Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

FBXO2 (6)

Publications

No (6)

Tag

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (3)

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Human FBXO2 Protein (Recombinant His) - LS-G2966

Source:

E. coli

Tag:

His

Price:

50 µg/$361; 250 µg/$739; 10 µg/$261

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Human FBXO2 Protein (Recombinant GST) (Full Length) - LS-G33130

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

58.3 kDa

Price:

10 µg/$479; 25 µg/$670

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Human FBXO2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68624

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.1 kDa

Price:

20 µg/$1,107

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Human FBXO2 Protein (Recombinant GST, N-terminus) (aa1-296) - LS-G57002

Source:

E. coli

Tag:

GST, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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FBXO2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114611

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.1 kDa

Price:

100 µg/$494

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Human FBXO2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82639

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.1 kDa

Price:

20 µg/$150

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