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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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FBXL5 / FBL5
F-box and leucine-rich repeat protein 5
FBXL5 / FBL5 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternatively spliced transcript variants have been described for this locus.
| Gene Name: | F-box and leucine-rich repeat protein 5 |
| Family/Subfamily: | F-Box |
| Synonyms: | FBXL5, FBL5, F-box protein FBL4/FBL5, FLR1, p45SKP2-like protein, F-box protein FBL5, F-box/LRR-repeat protein 5, FBL4 |
| Target Sequences: | AF176700 AAF03700.1 Q9UKA1 |
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