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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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FAT1 / FAT

FAT atypical cadherin 1

FAT1 / FAT is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described.

Gene Name: FAT atypical cadherin 1
Family/Subfamily: Cadherin , not assigned-Cadherin
Synonyms: FAT1, Cadherin ME5, CDHF7, CDHR8, FAT, FAT tumor suppressor 1, FAT tumor suppressor, HFat1, Protein fat homolog, Protocadherin Fat 1, Cadherin family member 7, Fat 1 cadherin, Fath, Hfat, ME5
Target Sequences: NM_005245 NP_005236.2 Q14517

Filtered By: None
Target
FAT1 / FAT (5)
Reactivity
Human (5)
Mouse (1)
Dog (1)
Application
IHC (3)
IHC-P (1)
WB (3)
ELISA (2)
Peptide-ELISA (1)
Host
rabbit (4)
mouse (1)
Isotype
IgG (2)
IgG1,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (4)
Clone
1634CT464.1.9 (1)
Format
Unconjugated (5)
Epitope
aa4203-4539 (1)
aa4450-4500 (1)
aa4484-4534 (1)
Publications
No (5)
Showing 1-5 of 5 results

FAT1 / FAT Antibody (aa4450-4500) IHC-plus™ LS-B13408
Rabbit Polyclonal to Human FAT1 / FAT
Mouse, Dog, Human
IHC IHC-P WB
Unconjugated
50µl 1mg/ml  $425.00
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Detection of Human and Mouse FAT1 by Western Blot. Samples: Whole cell lysate (50 ug) prepared using NETN buffer from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-FAT1 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Detection of Human and Mouse FAT1 by Western Blot. Samples: Whole cell lysate (50 ug) prepared using NETN buffer from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-FAT1 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

FAT1 / FAT Antibody LS-C406393
Rabbit Polyclonal (IgG) to Human FAT1 / FAT
Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human brain using FAT1 Polyclonal Antibody at dilution of 1:20.
Immunohistochemistry of Human brain using FAT1 Polyclonal Antibody at dilution of 1:20.

FAT1 / FAT Antibody LS-C403151
Rabbit Polyclonal (IgG) to Human FAT1 / FAT
Human
ELISA IHC
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human thyroid cancer using FAT1 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of Human thyroid cancer using FAT1 Polyclonal Antibody at dilution of 1:40.

FAT1 / FAT Antibody (aa4203-4539, clone 1634CT464.1.9) LS-C392598
Mouse Monoclonal [clone 1634CT464.1.9] (IgG1,k) to Human FAT1 / FAT
Human
Peptide-ELISA WB
Unconjugated
50µl  $205.00; 200µl  $305.00
Anti-FAT1 Antibody at 1:2000 dilution + recombinant protein Lysates/proteins at 20 ug per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 506 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Anti-FAT1 Antibody at 1:2000 dilution + recombinant protein Lysates/proteins at 20 ug per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1:10000 dilution. Predicted band size: 506 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.

FAT1 / FAT Antibody (aa4484-4534) LS-C291040
Rabbit Polyclonal to Human FAT1 / FAT
Human
WB
Unconjugated
100µl 1mg/ml  $395.00
Detection of Human FAT1 by Western Blot. Samples: Whole cell lysate (50 ug) prepared using NETN buffer from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-FAT1 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Detection of Human FAT1 by Western Blot. Samples: Whole cell lysate (50 ug) prepared using NETN buffer from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-FAT1 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Showing 1-5 of 5 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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