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FASN / Fatty Acid Synthase
fatty acid synthase
The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
| Gene Name: | fatty acid synthase |
| Synonyms: | FASN, Fatty acid synthase, OA-519, SDR27X1 |
| Target Sequences: | NM_004104 NP_004095.4 P49327 |
Publications (8)
1
FAS inhibitor cerulenin reduces food intake and melanocortin receptor gene expression without modulating the other (an)orexigenic neuropeptides in chickens. Dridi S, Ververken C, Hillgartner FB, Arckens L, Lutgarde A, Van der Gucht E, Cnops L, Decuypere E, Buyse J. American journal of physiology. Regulatory, integrative and comparative physiology. 2006 291:R138-47.
[PubMed:16455759]
2
Androgen deprivation increases p300 expression in prostate cancer cells. Heemers HV, Sebo TJ, Debes JD, Regan KM, Raclaw KA, Murphy LM, Hobisch A, Culig Z, Tindall DJ. Cancer research. 2007 67:3422-30.
[PubMed:17409453]
3
1-11C-acetate as a PET radiopharmaceutical for imaging fatty acid synthase expression in prostate cancer. Vvere AL, Kridel SJ, Wheeler FB, Lewis JS. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2008 49:327-34.
[PubMed:18199615]
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Products
ELISA Kits
(27)
Type
Custom
(4)
Development Kit
(1)
Sandwich
(19)
Sandwich CLIA
(3)
Target
FASN / Fatty Acid Synthase
(27)
Reactivity
Human
(6)
Mouse
(6)
Rat
(6)
Chicken
(4)
Guinea pig
(1)
Monkey
(1)
Porcine
(1)
Rabbit
(1)
Product Group
DevKit DuoPlus
(1)
Format
12 x 8-Well Microstrips
(2)
96-Well Microplate
(3)
96-Well Strip Plate
(21)
Antibody Pair and Standard
(1)
Publications
No
(27)
Sample Type
Cell Lysates
(1)
Plasma
(17)
Serum
(17)
Tissue Homogenates
(8)
Sandwich
96-Well Microplate
Human
0.31 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$834
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Microplate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$854
Sandwich
96-Well Strip Plate
Chicken
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Sandwich
96-Well Strip Plate
Porcine
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Sandwich
96-Well Strip Plate
Guinea pig
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Sandwich
96-Well Strip Plate
Rabbit
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Strip Plate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$929
Sandwich
96-Well Strip Plate
Mouse
50 - 1000 µg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
Sandwich
96-Well Microplate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Sandwich CLIA
96-Well Strip Plate
Chicken
5.49 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$1,034
Sandwich
96-Well Strip Plate
Human
2.5 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
Sandwich CLIA
12 x 8-Well Microstrips
Rat
62.5 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
Sandwich
96-Well Strip Plate
Rat
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$958
Development Kit
Antibody Pair and Standard
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
500 Wells/$1,120; 1000 Wells/$1,642
Sandwich
96-Well Strip Plate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$893
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