FAM125B

multivesicular body subunit 12B

FAM125B is a component of the ESCRT-I complex, a heterotetramer, which mediates the sorting of ubiquitinated cargo protein from the plasma membrane to the endosomal vesicle. ESCRT-I complex plays an essential role in HIV budding and endosomal protein sorting. Depletion and overexpression of this and related protein (MVB12A) inhibit HIV-1 infectivity and induce unusual viral assembly defects, indicating a role for MVB12 subunits in regulating ESCRT-mediated virus budding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Proteins (6)

Type

Over-Expression Lysate (4)

Recombinant (2)

Target

FAM125B (6)

Publications

No (6)

Tag

GST (1)

Myc-DDK (Flag) (5)

Species

Human (4)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Purification

Purified (1)

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FAM125B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121800

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.3 kDa

Price:

100 µg/$494

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FAM125B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108212

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.4 kDa

Price:

100 µg/$494

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Human FAM125B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G86328

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.3 kDa

Price:

20 µg/$150

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Human FAM125B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G86329

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.4 kDa

Price:

20 µg/$150

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Human FAM125B Protein (Recombinant GST) (Full Length) - LS-G35942

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

50.9 kDa

Price:

10 µg/$479; 25 µg/$670

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Human FAM125B Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G70132

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.3 kDa

Price:

20 µg/$1,107

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