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FABP3 / H-FABP

fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)

The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer.

Gene Name: fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
Synonyms: FABP3, H-FABP, Fatty acid-binding protein 3, M-FABP, MDGI, O-FABP, FABP11, Fatty acid binding protein 11
Target Sequences: NM_004102 NP_004093.1 P05413

Publications (1)

1
Exercise training-induced improvement in skeletal muscle PGC-1a-mediated fat metabolism is independent of dietary glycemic index. Mulya A, Haus JM, Solomon TP, Kelly KR, Malin SK, Rocco M, Barkoukis H, Kirwan JP. Obesity (Silver Spring, Md.). 2017 April;25:721-729. (Human) [Full Text Article] [PubMed:28349667] [PMC:PMC5373498]

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).