F8 / FVIII / Factor VIII

coagulation factor VIII, procoagulant component

F8 / FVIII / Factor VIII is coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.

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Products

Proteins (9)

Type

Recombinant (9)

Target

F8 / FVIII / Factor VIII (9)

Publications

No (9)

Tag

GST (1)

GST, N-terminus (1)

His (3)

His, C-Terminal (1)

His, N-Terminal (3)

Species

Dog (1)

Human (6)

Mouse (1)

Pig (1)

Source

E. coli (7)

Wheat Germ Extract (2)

Purification

Purified (3)

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Human F8 / FVIII / Factor VIII Protein (Recombinant His, C-Terminal) (aa1887-2044) - LS-G14405

Source:

E. coli

Tag:

His, C-Terminal

Molecular Weight:

20.1 kDa

Price:

10 µg/$249; 50 µg/$307; 200 µg/$482; 1 mg/$1,325; 5 mg/$2,204; 2 mg/$1,480

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Mouse F8 / FVIII / Factor VIII Protein (Recombinant His) (aa1854-1988) - LS-G14409

Source:

E. coli

Tag:

His

Molecular Weight:

17.6 kDa

Price:

10 µg/$281; 50 µg/$440; 100 µg/$702; 200 µg/$877; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170

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Human F8 / FVIII / Factor VIII Protein (Recombinant His, N-Terminal) (Phe2253-Glu2346) - LS-G14406

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

16.2 kDa

Price:

10 µg/$274; 50 µg/$400; 100 µg/$637; 200 µg/$797; 1 mg/$1,870; 500 µg/$1,424; 5 mg/$2,832; 2 mg/$2,053

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Pig F8 / FVIII / Factor VIII Protein (Recombinant His) (aa1669-1824) - LS-G14411

Source:

E. coli

Tag:

His

Molecular Weight:

45.3 kDa

Price:

10 µg/$289; 50 µg/$490; 100 µg/$782; 200 µg/$977; 1 mg/$2,114; 500 µg/$1,640; 5 mg/$3,417; 2 mg/$2,304

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Human F8 / FVIII / Factor VIII Protein (Recombinant His, N-Terminal) (Arg2-Tyr216) - LS-G136055

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

25 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365

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Human F8 / FVIII / Factor VIII Protein (Recombinant His, N-Terminal) - LS-G144718

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

24.5 kDa

Price:

50 µg/$419

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Human F8 / FVIII / Factor VIII Protein (Recombinant GST) (Full Length) - LS-G28415

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

51 kDa

Price:

2 µg/$439

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Human F8 / FVIII / Factor VIII Protein (Recombinant GST, N-terminus) (aa213-312) - LS-G58517

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Dog F8 / FVIII / Factor VIII Protein (Recombinant His) (aa2191-2337) - LS-G14404

Source:

E. coli

Tag:

His

Molecular Weight:

18.2 kDa

Price:

10 µg/$287; 50 µg/$480; 100 µg/$767; 200 µg/$957; 1 mg/$2,089; 500 µg/$1,617; 5 mg/$3,347; 2 mg/$2,278

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