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F7 / Factor VII

coagulation factor VII (serum prothrombin conversion accelerator)

F7 / Factor VII is coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Name: coagulation factor VII (serum prothrombin conversion accelerator)
Family/Subfamily: Protease , Serine S1
Synonyms: F7, Coagulation factor VII, Eptacog alfa, F7 Deficiency, Factor 7, Factor VIIa, FVII coagulation protein, Factor VII, FVII, SPCA, Factor VII Deficiency, Proconvertin
Target Sequences: NM_000131 NP_000122.1 P08709

☰ Filters
Products
Proteins (17)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (3)
Recombinant (13)
F7 / Factor VII (17)
No (17)
6His-SUMO, N-terminus (1)
GST (1)
GST, N-terminus (1)
His (4)
His, N-Terminal (3)
His,C-terminus (1)
His-GST (2)
His-T7 (1)
Myc-DDK (Flag) (3)
Bovine (1)
Human (9)
Mouse (2)
Rabbit (1)
Rat (3)
293T Cells (1)
E. coli (9)
HEK 293 Cells (5)
Wheat Germ Extract (2)
Purified (2)
Low endotoxin level (1)
F7 / Factor VII Protein - Recombinant Coagulation Factor VII By SDS-PAGE
Select
E. coli
His
14.7 kDa
10 µg/$292; 50 µg/$512; 100 µg/$817; 200 µg/$1,018; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359
Select
HEK 293 Cells
His, N-Terminal
~45 kDa
100 µg/$298
Select
HEK 293 Cells
His, N-Terminal
~45 kDa
200 µl/$283
F7 / Factor VII Protein - 12.5% SDS-PAGE of human F7 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
75.7 kDa
10 µg/$479; 25 µg/$670
F7 / Factor VII Protein - Recombinant  Coagulation Factor VII By SDS-PAGE
Select
E. coli
His-T7
20.9 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
F7 / Factor VII Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
28 kDa
20 µg/$215
F7 / Factor VII Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
6His-SUMO, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
F7 / Factor VII Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
F7 / Factor VII Protein - Purified recombinant protein F7 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
28 kDa
20 µg/$1,107
F7 / Factor VII Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
28 kDa
100 µg/$710
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
46.5 kDa
20 µg/$721
F7 / Factor VII Protein - Active Coagulation Factor VII (F7) by WB
Select
E. coli
His, N-Terminal
14kDa
10 µg/$385; 50 µg/$962; 200 µg/$1,623; 100 µg/$1,388; 1 mg/$3,073; 500 µg/$2,450; 5 mg/$6,721; 2 mg/$3,585
F7 / Factor VII Protein - Recombinant Coagulation Factor VII By SDS-PAGE
Select
E. coli
His
14.7 kDa
10 µg/$270; 50 µg/$372; 100 µg/$592; 200 µg/$742; 1 mg/$1,786; 500 µg/$1,352; 5 mg/$2,742; 2 mg/$1,966
F7 / Factor VII Protein - Recombinant Coagulation Factor VII By SDS-PAGE
Select
E. coli
His-GST
41.8 kDa
10 µg/$292; 50 µg/$512; 100 µg/$817; 200 µg/$1,018; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359
F7 / Factor VII Protein - Recombinant Coagulation Factor VII By SDS-PAGE
Select
E. coli
His
14.7 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
F7 / Factor VII Protein - Recombinant Coagulation Factor VII By SDS-PAGE
Select
E. coli
His-GST
59.5 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
F7 / Factor VII Protein - Recombinant Coagulation Factor VII By SDS-PAGE
Select
E. coli
His
16.2 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).