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F3 / CD142 / Tissue factor

coagulation factor III (thromboplastin, tissue factor)

F3 / CD142 / Tissue factor is coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described. Alternate splicing results in multiple transcript variants.

Gene Name: coagulation factor III (thromboplastin, tissue factor)
Synonyms: F3, CD142, CD142 antigen, TFA, Tissue factor, Thromboplastin, Coagulation factor III
Target Sequences: NM_001993 NP_001984.1 P13726

Publications (4)

1
Chloroquine reduces hypercoagulability in pancreatic cancer through inhibition of neutrophil extracellular traps. Boone BA, Murthy P, Miller-Ocuin J, Doerfler WR, Ellis JT, Liang X, Ross MA, Wallace CT, Sperry JL, Lotze MT, Neal MD, Zeh HJ 3rd. BMC cancer. 2018 June;18:678. [Full Text Article] [PubMed:29929491] [PMC:PMC6013899]
2
Procoagulant extracellular vesicles in amniotic fluid. Lena Hell, Lukas Wisgrill, Cihan Ay, Andreas Spittler, Michael Schwameis, Bernd Jilma, Ingrid Pabinger, Peter Altevogt, Johannes Thaler. Translational research : the journal of laboratory and clinical medicine. 2017 June;184:12-20.e1. [Full Text Article] [PubMed:28236427] [PMC:PMC6544525]
3
Using annexin V-coated magnetic beads to capture active tissue factor-bearing microparticles from body fluids. Frank Gieseler, Hans Gamperl, Frederike Theophil, Inga Stenzel, Tabea Quecke, Hendrik Ungefroren, Hendrik Lehnert. Cell biology international. 2014 Feburary;38:277-81. [Full Text Article] [PubMed:24431236]
4
Mammalian adipogenesis regulator (Areg) cells use retinoic acid signalling to be non- and anti-adipogenic in age-dependent manner. Magda Zachara , Pernille Y Rainer , Horia Hashimi , Julie M Russeil, Daniel Alpern, Radiana Ferrero, Maria Litovchenko, Bart Deplancke. The EMBO journal. 2022 September;41:e108206. [Full Text Article] [PubMed:35996853] [PMC:PMC9475530]
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Products
ELISA Kits (33)
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F3 / CD142 / Tissue factor (33)
Human (12)
Mouse (8)
Rat (7)
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Pig (1)
Rabbit (3)
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12 x 8-Well Microstrips (2)
96-Well Microplate (10)
96-Well Strip Plate (20)
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Adherent Cell Cultures (2)
Cell Culture Supernatants (7)
Cell Lysates (7)
Plasma (29)
Serum (23)
Tissue Homogenates (6)
Urine (2)
F3 / CD142 / Tissue factor ELISA Kit
Select
Sandwich
96-Well Microplate
Human
6.14 - 1500 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$700
F3 / CD142 / Tissue factor ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
F3 / CD142 / Tissue factor ELISA Kit
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Sandwich
96-Well Microplate
Mouse
6.25 - 400 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
F3 / CD142 / Tissue factor ELISA Kit
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Sandwich
96-Well Microplate
Rabbit
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$627
F3 / CD142 / Tissue factor ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
F3 / CD142 / Tissue factor ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Mouse
2.74 - 2000 pg/ml
Chemiluminescent
Plasma
1 Plate/$990
F3 / CD142 / Tissue factor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$818
F3 / CD142 / Tissue factor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$782
F3 / CD142 / Tissue factor ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$685
F3 / CD142 / Tissue factor ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
F3 / CD142 / Tissue factor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Urine
1 Plate/$717
F3 / CD142 / Tissue factor ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Rat
12.5 - 800 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
F3 / CD142 / Tissue factor ELISA Kit
Select
Sandwich
96-Well Microplate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Urine
1 Plate/$795
F3 / CD142 / Tissue factor ELISA Kit
Select
Sandwich
96-Well Microplate
Human
7.813 - 500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
F3 / CD142 / Tissue factor ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
F3 / CD142 / Tissue factor ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
F3 / CD142 / Tissue factor ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Human
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
F3 / CD142 / Tissue factor ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Human
2.74 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$968
F3 / CD142 / Tissue factor ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
F3 / CD142 / Tissue factor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
7.813 - 500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
F3 / CD142 / Tissue factor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum
1 Plate/$717
F3 / CD142 / Tissue factor ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Rabbit
12.5 - 800 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Tissue Homogenates
500 Wells/$1,254; 1000 Wells/$1,867
F3 / CD142 / Tissue factor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
6.25 - 400 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
F3 / CD142 / Tissue factor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
F3 / CD142 / Tissue factor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Horse
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).