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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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F13A1 / Factor XIIIa

coagulation factor XIII, A1 polypeptide

F13A1 / Factor XIIIa is the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion.

Gene Name: coagulation factor XIII, A1 polypeptide
Synonyms: F13A1, Coagulation factor XIIIa, Factor XIIIa, Fibrinoligase, FSF, A subunit, Transglutaminase. plasma, Transglutaminase A chain, F13A, TGASE
Target Sequences: NM_000129 NP_000120.2 P00488

Filtered by: None
Type
Custom (7)
Sandwich (10)
Sandwich CLIA (1)
Target
F13A1 / Factor XIIIa (18)
Reactivity
Human (7)
Mouse (3)
Rat (3)
Chicken (1)
Monkey (1)
Porcine (1)
Rabbit (1)
Sample Type
Cell Culture Supernatants (1)
Cell Lysates (1)
Plasma (11)
Serum (9)
Tissue Homogenates (3)
Publications
No (18)
Showing 1-18 of 18 results

Human F13A1 / Factor XIIIa ELISA Kit (Sandwich ELISA) - LS-F4425
Sandwich
96-Well Strip Plate
Human
0.188 - 12 ng/ml
Colorimetric - 450nm (TMB)
Plasma
1plate  $740.00
LSBio image for ELISA Kit

Human F13A1 / Factor XIIIa ELISA Kit (Sandwich ELISA) - LS-F11403
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $700.00
LSBio image for ELISA Kit

Human F13A1 / Factor XIIIa ELISA Kit (Sandwich ELISA) - LS-F23359
Sandwich
96-Well Microplate
Human
18.75 - 1200 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $590.00
LSBio image for ELISA Kit

Rat F13A1 / Factor XIIIa ELISA Kit (Sandwich ELISA) - LS-F8486
Sandwich
96-Well Strip Plate
Rat
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma
1plate  $690.00
LSBio image for ELISA Kit

Human F13A1 / Factor XIIIa ELISA Kit (Sandwich ELISA) - LS-F26870
Sandwich
96-Well Strip Plate
Human
100 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $870.00
LSBio image for ELISA Kit

Rat F13A1 / Factor XIIIa ELISA Kit (Custom ELISA) - LS-F15010
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1plate  $700.00
LSBio image for ELISA Kit

Mouse F13A1 / Factor XIIIa ELISA Kit (Custom ELISA) - LS-F15011
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1plate  $700.00
LSBio image for ELISA Kit

Bovine F13A1 / Factor XIIIa ELISA Kit (Custom ELISA) - LS-F15012
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1plate  $700.00
LSBio image for ELISA Kit

Human F13A1 / Factor XIIIa ELISA Kit (CLIA) - LS-F29567
Sandwich CLIA
12 x 8-Well Microstrips
Human
12.5 - 800 pg/ml
Chemiluminescent
Plasma, Serum
1plate  $700.00
LSBio image for ELISA Kit

Human F13A1 / Factor XIIIa ELISA Kit (Sandwich ELISA) - LS-F32824
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate  $790.00
LSBio image for ELISA Kit

Porcine F13A1 / Factor XIIIa ELISA Kit (Custom ELISA) - LS-F42476
Custom
96-Well Strip Plate
Porcine
18.75 - 1200 pg/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Monkey F13A1 / Factor XIIIa ELISA Kit (Custom ELISA) - LS-F42474
Custom
96-Well Strip Plate
Monkey
18.75 - 1200 pg/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Chicken F13A1 / Factor XIIIa ELISA Kit (Custom ELISA) - LS-F42473
Custom
96-Well Strip Plate
Chicken
0.938 - 60 pg/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Rabbit F13A1 / Factor XIIIa ELISA Kit (Custom ELISA) - LS-F42475
Custom
96-Well Strip Plate
Rabbit
0.75 - 48 pg/ml
Colorimetric - 450nm (TMB)
1plate  $660.00
LSBio image for ELISA Kit

Mouse F13A1 / Factor XIIIa ELISA Kit (Sandwich ELISA) - LS-F50967
Sandwich
96-Well Strip Plate
Mouse
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1plate  $870.00
LSBio image for ELISA Kit

Rat F13A1 / Factor XIIIa ELISA Kit (Sandwich ELISA) - LS-F51041
Sandwich
96-Well Strip Plate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $1,050.00
LSBio image for ELISA Kit

Human F13A1 / Factor XIIIa ELISA Kit (Sandwich ELISA) - LS-F54776
Sandwich
96-Well Strip Plate
Human
0.625 - 40 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1plate  $975.00
LSBio image for ELISA Kit

Mouse F13A1 / Factor XIIIa ELISA Kit (Sandwich ELISA) - LS-F55143
Sandwich
96-Well Strip Plate
Mouse
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1plate  $650.00
LSBio image for ELISA Kit
Showing 1-18 of 18 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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