F13A1 / Factor XIIIa

coagulation factor XIII, A1 polypeptide

F13A1 / Factor XIIIa is the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion.

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Products

ELISA Kits (19)

Type

Custom (2)

Development Kit (1)

Sandwich (15)

Sandwich CLIA (1)

Target

F13A1 / Factor XIIIa (19)

Reactivity

Human (7)

Mouse (4)

Rat (3)

Chicken (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Product Group

DevKit DuoPlus (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (16)

Antibody Pair and Standard (1)

Publications

No (19)

Sample Type

Cell Culture Supernatants (2)

Cell Lysates (2)

Plasma (13)

Serum (11)

Tissue Homogenates (4)

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Human F13A1 / Factor XIIIa (Sandwich ELISA) ELISA Kit - LS-F23359

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

18.75 - 1200 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human F13A1 / Factor XIIIa (Sandwich ELISA) ELISA Kit - LS-F4425

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.188 - 12 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$798

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Human F13A1 / Factor XIIIa (Sandwich ELISA) ELISA Kit - LS-F11403

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Mouse F13A1 / Factor XIIIa (Sandwich ELISA) ELISA Kit - LS-F15011

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

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Human F13A1 / Factor XIIIa (Sandwich ELISA) ELISA Kit - LS-F26870

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

100 - 2500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$913

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Mouse F13A1 / Factor XIIIa (Sandwich ELISA) ELISA Kit - LS-F55143

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.6 - 1000 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$818

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Rat F13A1 / Factor XIIIa (Sandwich ELISA) ELISA Kit - LS-F8486

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$856

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Rabbit F13A1 / Factor XIIIa (Sandwich ELISA) ELISA Kit - LS-F42475

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

0.75 - 48 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Monkey F13A1 / Factor XIIIa (Sandwich ELISA) ELISA Kit - LS-F42474

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

18.75 - 1200 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Porcine F13A1 / Factor XIIIa (Sandwich ELISA) ELISA Kit - LS-F42476

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

18.75 - 1200 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Chicken F13A1 / Factor XIIIa (Sandwich ELISA) ELISA Kit - LS-F42473

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

0.938 - 60 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Rat F13A1 / Factor XIIIa (Custom ELISA) ELISA Kit - LS-F15010

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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Bovine F13A1 / Factor XIIIa (Custom ELISA) ELISA Kit - LS-F15012

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Human F13A1 / Factor XIIIa (CLIA) ELISA Kit - LS-F29567

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

12.5 - 800 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Human F13A1 / Factor XIIIa (Sandwich ELISA) ELISA Kit - LS-F32824

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Rat F13A1 / Factor XIIIa (Sandwich ELISA) ELISA Kit - LS-F51041

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$870

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Human F13A1 / Factor XIIIa (Sandwich ELISA) ELISA Kit - LS-F54776

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$1,041

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Mouse F13A1 / Factor XIIIa (Sandwich ELISA) ELISA Kit - LS-F50967

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$870

Select

DevKit DuoPlus Mouse F13A1 / Factor XIIIa ELISA Development Kit - LS-F71742

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Mouse

Range:

3.12 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

500 Wells/$1,228; 1000 Wells/$1,823

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